{"title":"Advances on the etiology of bubble formation mechanism of altitude decompression sickness","authors":"Xiaohui Zheng, Qinglin Zhou, Zhaoli Ge, Feifei Wu","doi":"10.3760/CMA.J.ISSN.1007-6239.2019.01.015","DOIUrl":null,"url":null,"abstract":"Objective \nTo investigate the new research solutions on special environmental medicine by discussing the etiology of bubble formation mechanism in the basic researches of altitude decompression. \n \n \nLiterature resource and selection \nResearch papers and literature reviews published at home and abroad. \n \n \nLiterature quotation \nFifty-eight published papers and reviews were cited. \n \n \nLiterature synthesis \nThe role of air nucleus, the precursors of bubbles, in the etiology of decompression sickness was reviewed and analyzed including the normal existence of air nucleus in vivo, the mechanism of its formation and stable existence. At present, there is no definite conclusion on above three aspects and the researches are still facing the challenge. In addition, the relationship between bubble formation and pathological manifestations of decompression sickness, the effect of movement on bubble formation, the methodology of micro-bubble study in vivo, the role of patent foramen ovale in the pathogenesis of neuropathic decompression sickness, and the relationship and significance between bubble study in vivo and some subjects related to clinical medicine were discussed. The scope of this paper covers the main issues in the basic research of altitude decompression sickness, and has certain reference significance for understanding and planning the future research direction in this field. \n \n \nConclusions \nWith the help of interdisciplinary integration, the etiological study of decompression sickness is expected to make substantial breakthroughs and the research and development of special environmental medicine will have a new direction of solution. \n \n \nKey words: \nAltitude; Decompression sickness; Bubble; Gas nucleus; Review","PeriodicalId":9904,"journal":{"name":"中华航空航天医学杂志","volume":"1 1","pages":"72-78"},"PeriodicalIF":0.0000,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华航空航天医学杂志","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-6239.2019.01.015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To investigate the new research solutions on special environmental medicine by discussing the etiology of bubble formation mechanism in the basic researches of altitude decompression.
Literature resource and selection
Research papers and literature reviews published at home and abroad.
Literature quotation
Fifty-eight published papers and reviews were cited.
Literature synthesis
The role of air nucleus, the precursors of bubbles, in the etiology of decompression sickness was reviewed and analyzed including the normal existence of air nucleus in vivo, the mechanism of its formation and stable existence. At present, there is no definite conclusion on above three aspects and the researches are still facing the challenge. In addition, the relationship between bubble formation and pathological manifestations of decompression sickness, the effect of movement on bubble formation, the methodology of micro-bubble study in vivo, the role of patent foramen ovale in the pathogenesis of neuropathic decompression sickness, and the relationship and significance between bubble study in vivo and some subjects related to clinical medicine were discussed. The scope of this paper covers the main issues in the basic research of altitude decompression sickness, and has certain reference significance for understanding and planning the future research direction in this field.
Conclusions
With the help of interdisciplinary integration, the etiological study of decompression sickness is expected to make substantial breakthroughs and the research and development of special environmental medicine will have a new direction of solution.
Key words:
Altitude; Decompression sickness; Bubble; Gas nucleus; Review
期刊介绍：
The aim of Chinese Journal of Aerospace Medicine is to combine theory and practice, improve and popularize, actively advocate a hundred flowers bloom and a hundred schools of thought contend, advocate seeking truth from facts, promote the development of the related disciplines of aerospace medicine and human efficiency, and promote the exchange and penetration of aerospace medicine and human efficiency with other biomedical and engineering specialties.
Topics of interest for Chinese Journal of Aerospace Medicine include:
-The content of the journal belongs to the discipline of special medicine and military medicine, with the characteristics of multidisciplinary synthesis and cross-penetration, and mainly reflected in the aerospace industry, aerospace flight safety and efficiency, as well as the synthesis of special medicine, preventive medicine, environmental medicine, psychology, etc.
-Military aeromedicine (Air Force, Navy and Army aeromedicine) and civil aeromedicine, with a balance of aerospace medicine are the strengths of the journal.
-The change in aerospace medicine from a focus on promoting physiological compensatory adaptations to enhancing human performance under extreme environmental conditions is what the journal is helping to promote.
-The expansion of manuscripts in high altitude medicine is also a special emphasis of the journal.
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