exudative Age-Related Macular Degeneration: current Therapies and potential Treatments

P. Quiram, Yahui Song
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Abstract

Strategies for preventing vision loss in patients with neovascular age-related macular degeneration (ARMD) have evolved over the past decade. Whereas earlier treatments were based on thermal destruction of choroidal neovascularization (CNV), new therapies rely on targeted pharmacologic approaches to reduce the harmful effects of CNV treatment. For the first time in the history of neovascular ARMD treatment, anti-VEGF therapies have consistently improved visual acuity in a subset of patients. Clinical trials continue to investigate the optimal dosing strategies and combination therapies to better refine the treatment of this chronic and debilitating disease.
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渗出性年龄相关性黄斑变性:目前的治疗方法和潜在的治疗方法
在过去的十年中,预防新生血管性年龄相关性黄斑变性(ARMD)患者视力丧失的策略已经发生了变化。早期的治疗是基于脉络膜新生血管(CNV)的热破坏,而新的治疗方法依赖于靶向药物方法来减少脉络膜新生血管治疗的有害影响。在新血管性ARMD治疗史上,抗vegf疗法首次持续改善了一部分患者的视力。临床试验继续研究最佳剂量策略和联合疗法,以更好地改善这种慢性和衰弱性疾病的治疗。
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