Rosiglitazone, not only potentially protects myocardium against complications of type 2 diabetes mellitus but also induces myocardium infarction: Possible mechanisms?
Mingxiang Ye, Yuemin Wang, Xinliang Ma, Jianming Pei
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Abstract
Rosiglitazone is widely used to improve diabetes mellitus, but its adverse cardiovascular effect is recently recognized. The exact mechanism is still unknown. In this paper, we predict that rosiglitazone probably regulates the insulin gene expression, which cause complications in the long term use.
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