Chronic Oral Amiodarone as a Cause of Acute Liver Failure.

Evelyn Calderon-Martinez, Samanta Landazuri-Navas, Gizem Kaya, John Cinicola
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Abstract

Acute liver failure (ALF) is a rare condition that can have a variable clinical course and potentially fatal outcomes. Medication toxicity is a known etiology, however liver failure induced by amiodarone is rare and has been reported mostly in the setting of intravenous (IV) infusion. We present an 84-year-old patient who developed ALF after chronic use of oral amiodarone. The patient received supportive care and her symptoms improved.

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慢性口服胺碘酮可引起急性肝衰竭。
急性肝衰竭(ALF)是一种罕见的疾病,可以有一个可变的临床过程和潜在的致命的结果。药物毒性是一种已知的病因,然而胺碘酮引起的肝衰竭是罕见的,报道大多在静脉(IV)输注设置。我们报告了一位84岁的患者,在长期使用口服胺碘酮后发生ALF。患者接受支持性护理,症状得到改善。
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