{"title":"Identification for control of biomedical systems using a very short experiment","authors":"K. Soltesz, P. Mercader","doi":"10.1109/ICSMB.2016.7915107","DOIUrl":null,"url":null,"abstract":"This paper presents a combined experiment and identification procedure, well suited to obtain low-order dynamic models of a patients' response to continuous drug administration. The experiment requires no a priori information and is of very short duration. The identification method provides both a parametric low-order model, and an estimate of the parameter error covariance. It has been demonstrated to work well with very noisy measurements, as typically encountered in drug dosing applications.","PeriodicalId":90521,"journal":{"name":"IEEE International Conference on Systems Biology : [proceedings]. IEEE International Conference on Systems Biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE International Conference on Systems Biology : [proceedings]. IEEE International Conference on Systems Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICSMB.2016.7915107","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
This paper presents a combined experiment and identification procedure, well suited to obtain low-order dynamic models of a patients' response to continuous drug administration. The experiment requires no a priori information and is of very short duration. The identification method provides both a parametric low-order model, and an estimate of the parameter error covariance. It has been demonstrated to work well with very noisy measurements, as typically encountered in drug dosing applications.