Prevention and Treatment of Basic Diseases: A Potential Direction to Intervene Alzheimer’s Disease

Wei Jiangping, Xu Shijun
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Abstract

As the life span of human beings increases, the number of dementia patients such as Alzheimer’s disease (AD) is increasing. AD may be one of the major diseases faced by the whole world in the future. It is an unresponsive for single drug according to the current stage of AD pathogenesis and drug research. Combined use of various drugs may be the inevitable trend of AD drug research in the future. Personalized treatment of metabolic diseases, vascular diseases and chronic inflammatory risk diseases is a necessary step to intervene in AD. During the middle age, to strengthen immunity and to reduce the external environment to stimulate the susceptible gene, which is beneficial to suppress the formation of AD. In a word, the early prevention of AD is better than the later treatment.
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基础疾病的防治:干预阿尔茨海默病的潜在方向
随着人类寿命的延长,阿尔茨海默病(AD)等痴呆症患者也在增加。AD可能是未来全世界面临的主要疾病之一。从目前的发病机制和药物研究来看,属于单药无应答。多种药物联合使用可能是未来AD药物研究的必然趋势。代谢性疾病、血管疾病和慢性炎症危险疾病的个性化治疗是干预AD的必要步骤。人到中年,增强免疫力,减少外界环境对易感基因的刺激,有利于抑制AD的形成。总之,AD的早期预防比后期治疗好。
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