Screening and guided self-help intervention for anxiety and depression in patients with type 2 diabetes

JAC Meeuwissen MSc, GJM Holleman RN, MSc, FJ de Jong MD, J Nuyen PhD, CM van der Feltz-Cornelis MD, PhD, MSc
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引用次数: 17

Abstract

Strategies for timely recognition and adequate treatment of mental disorder in diabetes are urgently needed. The aims of this study are to develop and evaluate an intervention for anxiety disorder and major depressive disorder (depression) in patients with type 2 diabetes (T2DM) by diabetes nurses (DNs) in primary care that requires minimal effort of all caregivers involved.

In this pilot, an open clinical study with pre-post test, seven trained DNs screened their patients. Patients screen-positive for anxiety disorder or depression underwent a standardised interview (MINI) by a researcher for validation. Patients fulfilling DSM-IV-TR criteria for anxiety disorder or depression were offered a self-help intervention supported and monitored by the DN in one-to-one guidance. Follow-up assessment was at six months.

Of 311 eligible patients, 111 consented to screening. Fifty-five patients were screened positive; 26 screen-positives were confirmed. Of the latter, 16 started and 15 completed the guided self-help intervention. Anxiety symptoms dropped 3.2 points (p=0.011), depressive symptoms 5.7 points (p=0.007), and somatic symptom severity 2.9 points (p=0.041) on the Patient Health Questionnaire. Diabetes-related negative emotions (PAID-NL) dropped 3.8 points (p=0.048). General functioning (EuroQol) improved by 14 points (p=0.007), and emotional role-functioning (SF-36) showed 33.4 points improvement (p=0.010). To conclude, trained DNs succeeded in screening and guiding a self-help intervention; mental and somatic symptoms, general functioning, and quality of life improved significantly.

This pilot strongly indicates that DNs can perform screening and one-to-one guidance regarding a self-help intervention for anxiety disorder and depression, playing an important role in the early detection and follow up of co-morbid mental disorders complicating diabetes. Copyright © 2011 FEND. Published by John Wiley & Sons, Ltd.

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2型糖尿病患者焦虑和抑郁的筛查和指导自助干预
迫切需要及时识别和适当治疗糖尿病精神障碍的策略。本研究的目的是开发和评估糖尿病护士(dn)在初级保健中对2型糖尿病(T2DM)患者的焦虑障碍和重度抑郁障碍(抑郁症)的干预措施,该干预措施需要所有护理人员的最小努力。在这项开放的临床试验中,7名训练有素的DNs筛选了他们的患者。焦虑障碍或抑郁症筛查阳性的患者接受研究者的标准化访谈(MINI)进行验证。满足DSM-IV-TR焦虑障碍或抑郁标准的患者在一对一指导下接受DN支持和监测的自助干预。6个月时进行随访评估。在311名符合条件的患者中,111名同意进行筛查。55例患者筛查呈阳性;确诊筛查阳性26例。在后者中,16人开始,15人完成了指导自助干预。患者健康问卷上焦虑症状下降3.2分(p=0.011),抑郁症状下降5.7分(p=0.007),躯体症状严重程度下降2.9分(p=0.041)。与糖尿病相关的负面情绪(PAID-NL)下降3.8分(p=0.048)。一般功能(EuroQol)改善了14分(p=0.007),情感角色功能(SF-36)改善了33.4分(p=0.010)。综上所述,训练有素的dn成功筛选和指导了自助干预;精神和躯体症状、一般功能和生活质量显著改善。本试点结果有力地表明,心理咨询师可以对焦虑障碍和抑郁进行筛查和一对一的自助干预指导,在糖尿病合并精神障碍的早期发现和随访中发挥重要作用。版权所有©2011中华生态科学研究院。John Wiley &出版;儿子,有限公司
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