Gram-negative infections in frail patients.

Q2 Medicine Infezioni in Medicina Pub Date : 2022-01-01 DOI:10.53854/liim-3101-5

Emanuele Rando, Elena Matteini, Silvia Guerriero, Massimo Fantoni

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Abstract

Introduction: Gram-negative infections (GNIs) are frequently encountered both in community and hospital settings. Frail patients, defined as elderly individuals with multiple comorbidities, are particularly vulnerable to them. The presentation and the course of GNIs differ in aged patients compared with younger ones, making their management a unique challenge. This review aimed to outline the essential elements of the presentation, diagnosis, and outcome of GNIs in frail individuals.

Methods: MEDLINE/PubMed library search was performed using the following terms: frail, frailty, elderly, Gram-negative, infections, pneumonia, urinary tract infection, and bloodstream infection for the purpose of the review.

Conclusions: Elderly patients with multimorbidity represent a distinct population with relevant differences in GNIs presentation, diagnosis, and outcome. Several pitfalls should be avoided and appropriately addressed when facing GNIs in this group of patients. Future studies focusing on this population should be encouraged.

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体弱病人的革兰氏阴性感染。

简介:革兰氏阴性感染(GNIs)经常在社区和医院环境中遇到。体弱的病人，定义为有多种合并症的老年人，特别容易受到它们的影响。与年轻患者相比，老年患者GNIs的表现和病程不同，使其管理成为一项独特的挑战。本综述旨在概述GNIs在体弱个体中的表现、诊断和结果的基本要素。方法:MEDLINE/PubMed图书馆检索使用以下术语:虚弱，虚弱，老年，革兰氏阴性，感染，肺炎，尿路感染和血流感染。结论:老年多病患者是一个独特的人群，在GNIs的表现、诊断和预后方面存在相关差异。当面对这组患者的gni时，应避免并适当处理几个陷阱。应该鼓励今后针对这一人群的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Infezioni in Medicina Medicine-Infectious Diseases

CiteScore

8.40

自引率

0.00%

发文量

期刊介绍： The Journal publishes original papers, in Italian or in English, on topics concerning aetiopathogenesis, prevention, epidemiology, diagnosis, clinical features and therapy of infections, whose acceptance is subject to the referee’s assessment. The Journal is of interest not only to infectious disease specialists, microbiologists and pharmacologists, but also to internal medicine specialists, paediatricians, pneumologists, and to surgeons as well. The Editorial Board includes experts in each of the above mentioned fields.