Monkeypox virus infection mimicking primary syphilis.

Q2 Medicine Infezioni in Medicina Pub Date : 2022-01-01 DOI:10.53854/liim-3101-16
Giulia Ciccarese, Antonio Di Biagio, Francesco Drago, Mario Mastrolonardo, Antonietta Pipoli, Sergio Lo Caputo, Gaetano Serviddio, Teresa Santantonio, Aurora Parodi
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引用次数: 17

Abstract

In our case series of monkeypox (MPX) virus infected patients, one had a single genital ulcer as the only cutaneous manifestation of the infection. Physical examination revealed a single, rounded ulcer of the shaft penis characterized by pinkish raised, infiltrated borders and a crusty yellowish bottom associated with bilateral inguinal lymphadenopathies. Serology for Treponema pallidum infection and a complete screening for sexually transmitted infections (STIs) resulted negative except for the detection of Staphylococcus aureus at the cultural examination and MPX DNA at the ulcer bottom. The patient's general conditions were good therefore he remained isolated at home for 3 weeks after the diagnosis. At one month follow up, he presented only a depressed pinkish skin scars on the site of the previous ulcer. The clinical presentation of this patient could easily be misdiagnosed with other sexually transmitted infections (STIs), especially with primary syphilis. MPX infection should be considered in the differential diagnosis of STIs, also in patients with weak and localized manifestations.

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猴痘病毒感染模拟初级梅毒。
在我们的猴痘(MPX)病毒感染患者的病例系列中,一名患者有单一生殖器溃疡作为感染的唯一皮肤表现。体格检查显示阴茎轴呈单一圆形溃疡,边界呈粉红色凸起,浸润,底部呈黄痂状,伴有双侧腹股沟淋巴结病变。梅毒螺旋体感染的血清学检查和性传播感染的全面筛查结果均为阴性,除了在培养检查中检测到金黄色葡萄球菌和在溃疡底部检测到MPX DNA。患者的一般情况良好,因此在诊断后他在家中隔离了3周。在一个月的随访中,他只在先前溃疡的部位出现了一个凹陷的粉红色皮肤疤痕。该患者的临床表现很容易被误诊为其他性传播感染,特别是原发性梅毒。在性传播感染的鉴别诊断中应考虑MPX感染,在表现较弱和局限性的患者中也是如此。
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Infezioni in Medicina
Infezioni in Medicina Medicine-Infectious Diseases
CiteScore
8.40
自引率
0.00%
发文量
62
期刊介绍: The Journal publishes original papers, in Italian or in English, on topics concerning aetiopathogenesis, prevention, epidemiology, diagnosis, clinical features and therapy of infections, whose acceptance is subject to the referee’s assessment. The Journal is of interest not only to infectious disease specialists, microbiologists and pharmacologists, but also to internal medicine specialists, paediatricians, pneumologists, and to surgeons as well. The Editorial Board includes experts in each of the above mentioned fields.
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