An Efficient Palladium-Thiourea Catalysed Heck Cross-Coupling Reaction for Molecular Electronic Interest

Abstract

The synthesis and utilization of C-C bonds formatio n are concerned about the key steps for the buildin g of several conducting molecular electronics involving many asy mmetric catalysts approached, which is an essential task that most researchers would ignore in preparing these materia ls to enhance the production yield of cross-couplin g materials. Despite the enormous progress, there still remains great demand for economic and practicable cross-c upling processes involving ultra-low catalyst loadings wit h high turnover numbers due to the employment of co nventional metal catalyst. Thus, there has been an excessive i nterest to cultivate non-phosphine palladium cataly s s for excellent achievement of activity, stability, and substrate t olerance which permit the coupling reactions to be conducted under mild reaction condition at ambient atmosphere. In t his contribution, N-(4-nitrophenylcarbamothioyl)-N’ -(4methylbenzoyl) thiourea ( LT1 ) and its metal complex of MLT1 featuring Pd (II) have been successfully character ised via typical spectroscopic methods namely; Infrared (IR) spectroscopy, Ultraviolet-visible (UV-Vis) spe ctroscopy, CHNS elemental analysis, and Nuclear Magnetic Reson ance ( H and C NMR). In turn, catalytic studies of palladium catalyst ( MLT1 ) were tested for its homogenous catalytic activity in Heck cross-coupling reaction. The reaction was monitored by Gas Chromatography-Flame Ionisation De tector (GC-FID). Results reveal that MLT1 exhibits 100% of conversion starting material into a cross-coupling product, which was alkene-based compound.