Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study.

IF 3.3 Q2 NUTRITION & DIETETICS BMJ Nutrition, Prevention and Health Pub Date : 2022-12-01 DOI:10.1136/bmjnph-2021-000408
Monique Tan, Feng He, Joan K Morris, Graham MacGregor
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引用次数: 11

Abstract

Introduction: In China, salt intake is among the highest in the world (~11 g/day) and cardiovascular disease (CVD) accounts for 40% of deaths. We estimated the potential impact of reducing salt intake on CVD events in China, via systolic blood pressure (SBP).

Methods: To develop our model, we extracted the effect of salt reduction on SBP from a meta-regression of randomised trials and a population study, and that of SBP on CVD risk from pooled cohort studies.

Results: Reducing population salt intake in China by 1 g/day could lower the risk for ischaemic heart disease by about 4% (95% uncertainty interval 1.8%-7.7%) and the risk for stroke by about 6% (2.4%-9.3%). Should this reduced salt level be sustained until 2030,~9 million (M) (7M-10.8M) CVD events could be prevented, of which ~4M (3.1M-4.9M) would have been fatal. Greater and gradual salt intake reductions, to achieve WHO's target of 30% reduction by 2025 or the Chinese government's target of ≤5 g/day by 2030, could prevent ~1.5 or 2 times more CVD events and deaths, respectively. Should the prolonged effect of salt reduction over several years be accounted for, all estimates of CVD events and deaths prevented would be 25% greater on average.

Conclusion: Bringing down the high salt intake levels in China could result in large reductions in CVD. An easily achievable reduction of 1 g/day could prevent ~9M CVD events by 2030. Urgent action must be taken to reduce salt intake in China.

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一项模型研究:到2030年,中国每天减少1克盐摄入量可以预防近900万例心血管疾病。
在中国,盐的摄入量是世界上最高的(~11克/天),心血管疾病(CVD)占死亡人数的40%。我们通过收缩压(SBP)估计了减少盐摄入量对中国CVD事件的潜在影响。方法:为了建立我们的模型,我们从随机试验和人群研究的荟萃回归中提取了盐减少对收缩压的影响,并从合并队列研究中提取了收缩压对心血管疾病风险的影响。结果:中国人群盐摄入量每减少1 g/d,可使缺血性心脏病风险降低约4%(95%不确定区间为1.8%-7.7%),卒中风险降低约6%(2.4%-9.3%)。如果这种降低的盐水平持续到2030年,大约900万(M)(700 - 1080万)例心血管疾病可以预防,其中大约400万(310 - 490万)例将是致命的。为了实现世卫组织到2025年减少30%的目标或中国政府到2030年减少≤5克/天的目标,更大程度和逐步减少盐摄入量可分别使心血管疾病事件和死亡人数增加1.5倍或2倍。如果考虑到几年来减少盐摄入的长期效果,所有心血管疾病事件和预防死亡的估计将平均增加25%。结论:降低中国高盐摄入水平可能导致心血管疾病的大幅减少。如果每天减少1克,到2030年可以预防约900万例心血管疾病。中国必须采取紧急行动减少盐的摄入量。
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来源期刊
BMJ Nutrition, Prevention and Health
BMJ Nutrition, Prevention and Health Nursing-Nutrition and Dietetics
CiteScore
5.80
自引率
0.00%
发文量
34
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