Diuretic activity of Sambucus nigraL. ssp. palmensis(Link) R. Bolli, an endemic Canary Islands species

IF 0.7 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-07-30 DOI:10.37360/blacpma.23.22.4.37

Sandra Devora Gutierrez, F. Hernández-Luis, D. Martin-Herrera, Chaxiraxi C. Morales-Marrero, S. Abdala

引用次数: 0

Abstract

o determine the diuretic activity of Sambucus nigraL. ssp. palmensis(Link) R. Bolli (SP). SP was evaluated in adult female Swiss mice. Urinary excretion volume was measured and the concentration of sodium, potassium, chloride, pH and specific conductance of 3 doses of aqueous extract (35.0, 52.2 and 70.0 mg kg-1) were determined. SP (70.0 mg kg-1) produced ahigher urinary excretion (6.41 mL) and diuretic index (15%) than hydrochlorothiazide (HCTZ) (6.27 mLand 12%, respectively). The saluretic index indicates a lower sodium excretion than HCTZ (13%) and inversely proportional to the dose (8% -5%). The same is observed for potassium excretion (0.0172-0.0162 mEq.K+/100 g/6 h), which achieves a lower value than the control group (0.0166 mEq.K+/100 g/6 h), suggesting potassium retention. These results support the use of this plant species as a diuretic in Canarian folk medicine.

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黑参的利尿作用。ssp。棕榈属(Link) R. Bolli，加那利群岛特有种

测定黑参的利尿活性。ssp。(链接)R. Bolli (SP)。对成年雌性瑞士小鼠进行SP评价。测定尿排泄量，测定3个剂量(35.0、52.2和70.0 mg kg-1)水提液的钠、钾、氯浓度、pH和比电导。SP (70.0 mg kg-1)的尿量(6.41 mL)和利尿指数(15%)均高于氢氯噻嗪(HCTZ) (6.27 mL和12%)。降盐指数表明钠排泄量低于HCTZ(13%)，与剂量成反比(8% -5%)。钾排泄量(0.0172-0.0162 mEq)也有相同的结果。K+/100 g/6 h)，低于对照组(0.0166 mEq)。K+/100 g/6 h)，提示钾潴留。这些结果支持该植物在加那利民间医学中作为利尿剂的使用。

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来源期刊

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas PHARMACOLOGY & PHARMACY-

CiteScore

1.30

自引率

14.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas (BLACPMA), [Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants]; currently edited by the publishing house MS-Editions, is a bi-monthly international publication that publishes original peerreviewed research in the field of medicinal and aromatic plants, with nearly 20 years of experience. BLACPMA is a scientific journal that publishes two types of articles: Reviews (only in English) and Original Articles (Spanish or English), its main lines of action being agronomy, anthropology and ethnobotany, industrial applications, botany, quality and standardization, ecology and biodiversity, pharmacology, phytochemistry, pharmacognosy, regulatory and legislative aspects. While all areas of medicinal plants are welcome and the experimental approaches used can be broad and interdisciplinary; other areas of research that are not mentioned depend on the Editorial Committee for their acceptance.