Prognostic Value of Chest-Computed Tomography in Patients with COVID-19.

IF 1.8 Q3 RESPIRATORY SYSTEM Advances in respiratory medicine Pub Date : 2022-08-09 DOI:10.3390/arm90040041

Gökhan Perincek, Canver Önal, Timor Omar

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引用次数: 3

Abstract

Background: The diagnostic value for chest CT has been widely established in patients with COVID-19. However, there is a lack of satisfactory data about the prognostic value of chest CTs. This study investigated the prognostic value of chest CTs in COVID-19 patients. Materials and Methods: A total of 521 symptomatic patients hospitalized with COVID-19 were included retrospectively. Clinical, laboratory, and chest CT characteristics were compared between survivors and non-survivors. Concerning chest CT, for each subject, a semi-quantitative CT severity scoring system was applied. Results: Most patients showed typical CT features based on the likelihood of COVID-19. The global CT score was significantly higher in non-survivors (median (IQR), 1 (0−6) vs. 10 (5−13), p < 0.001). A cut-off value of 5.5 for the global CT score predicted in-hospital mortality with 74% sensitivity and 73% specificity. Global CT score, age, C-reactive protein, and diabetes were independent predictors of in-hospital mortality. The global CT score was significantly correlated with the C-reactive protein, D-dimer, pro-brain natriuretic peptide, and procalcitonin levels. Conclusion: The global CT score could provide valuable prognostic data in symptomatic patients with COVID-19.

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胸部ct对COVID-19患者预后的价值。

背景:胸部CT在COVID-19患者中的诊断价值已被广泛确立。然而，关于胸部ct的预后价值缺乏令人满意的数据。本研究探讨胸部ct对COVID-19患者的预后价值。材料与方法:回顾性分析521例有症状的新型冠状病毒肺炎住院患者。比较幸存者和非幸存者的临床、实验室和胸部CT特征。在胸部CT方面，对每个受试者采用半定量CT严重程度评分系统。结果:基于COVID-19的可能性，大多数患者表现出典型的CT特征。非幸存者的整体CT评分明显更高(中位数(IQR)， 1(0−6)比10(5−13)，p < 0.001)。总体CT评分的临界值为5.5，预测住院死亡率的敏感性为74%，特异性为73%。总体CT评分、年龄、c反应蛋白和糖尿病是院内死亡率的独立预测因子。总体CT评分与c反应蛋白、d -二聚体、前脑利钠肽和降钙素原水平显著相关。结论:CT整体评分可为有症状的COVID-19患者提供有价值的预后数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in respiratory medicine RESPIRATORY SYSTEM-

CiteScore

2.60

自引率

0.00%

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期刊介绍： "Advances in Respiratory Medicine" is a new international title for "Pneumonologia i Alergologia Polska", edited bimonthly and addressed to respiratory professionals. The Journal contains peer-reviewed original research papers, short communications, case-reports, recommendations of the Polish Respiratory Society concerning the diagnosis and treatment of lung diseases, editorials, postgraduate education articles, letters and book reviews in the field of pneumonology, allergology, oncology, immunology and infectious diseases. "Advances in Respiratory Medicine" is an open access, official journal of Polish Society of Lung Diseases, Polish Society of Allergology and National Research Institute of Tuberculosis and Lung Diseases.