Metabolic effects of naphthalene, toluene or phenol intoxication in the cichlid fish tilapia, Oreochromis mossambicus: Changes in aminotrasferase activities

Ajit D. Dangé
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引用次数: 10

Abstract

Exposure of the cichlid fish tilapia, Oreochromis mossambicus, to acutely stressful (96-h LC50) levels of naphthalene, toluene or phenol for 4 days did not produce any change in the activities of aspartate and alanine aminotransferases in liver or muscle. However, the stress of 10 weeks exposure to chronically sublethal (50% 24-h LC50) concentrations of the hydrocarbons stimulated the enzyme activities in both the tissues. This change was accompanied in some groups by reduced tissue levels of soluble proteins and free amino acids, suggesting increased tissue proteolysis in these sublethally stressed tilapia.

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罗非鱼(Oreochromis mossambicus)体内萘、甲苯或苯酚中毒的代谢影响:氨基转移酶活性的变化
罗非鱼(Oreochromis mossambicus)暴露于急性应激(96 h LC50)水平的萘、甲苯或苯酚中4天,肝脏或肌肉中天冬氨酸和丙氨酸转氨酶的活性没有任何变化。然而,暴露于慢性亚致死(50% 24小时LC50)浓度的碳氢化合物10周的应激刺激了两个组织中的酶活性。在某些组中,这种变化伴随着可溶性蛋白和游离氨基酸的组织水平降低,表明这些亚致死应激罗非鱼的组织蛋白水解增加。
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