Painful cellular angiofibroma of the vulva: case report

H. Shojaei, C. Albertin, A. Schaus, A. Al-Niaimi
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引用次数: 2

Abstract

Introduction Cellular angiofibroma is a rare benign mesenchymal tumour that occurs in the subepithelial myxoid stromal zone of the vulvovaginal region. We report a case of painful angiofibroma in a 52-year-old morbidly obese female, in the left labia. Case report A 52-year-old morbidly obese (body mass index of 67) female was referred to our gynaecologic oncology clinic with a 3-year history of a large, painful, pendulous left vulvar mass. Magnetic resonance imaging of the lesion helped confirm that the mass did not represent a hernia and was fibrous in nature. Resection revealed a 12 × 12 × 9 cm, a 187-gram encapsulated mass. Histologically, it was a well circumscribed tumour composed of hyalinised blood vessels and collagen bundles, exhibiting characteristic immunohistochemical features of a cellular angiofibroma. Conclusion Angiofibroma of the vulva is a rare benign encapsulated mass, yet hypervascular. Its diagnosis in a morbidly obese patient is challenging and necessitates magnetic resonance imaging or CT scan. Its surgical removal needs precision and meticulousness especially in a patient with multiple comorbidities.
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外阴疼痛性细胞血管纤维瘤1例
细胞血管纤维瘤是一种罕见的良性间质肿瘤,发生于外阴阴道区上皮下黏液样间质区。我们报告一例疼痛血管纤维瘤在一个52岁的病态肥胖女性,在左阴唇。病例报告一名52岁病态肥胖(身体质量指数67)女性,因左侧外阴巨大、疼痛、下垂肿块3年病史转介至妇科肿瘤诊所。病变的磁共振成像帮助确认肿块不代表疝,本质上是纤维性的。切除显示一个12 × 12 × 9厘米,187克的包被肿块。组织学上,它是一个界限分明的肿瘤,由透明化的血管和胶原束组成,表现出细胞性血管纤维瘤的典型免疫组织化学特征。结论外阴血管纤维瘤是一种少见的良性包膜性肿块,但存在血管增生。对病态肥胖患者的诊断具有挑战性,需要进行磁共振成像或CT扫描。其手术切除需要精确和细致,特别是在患者有多种合并症。
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