Antimicrobial activity ofTriclosancoated sutures in vitro

P. Saban, R. Gopal.
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Abstract

Introduction: Surgical site infections (S.S.I.) are most often due to the organisms present as indigenous flora and are a common problem in most of the hospitals. One of the risk factor is the presence of foreign material which includes suture. The use of antimicrobial coated sutures with the sustained action can be a useful supplement to the aseptic technique. Materials and methods: Randomly selected strains of MRSA, MRSE, Enterococcus, E.coli, Klebsiella & Pseudomonas species isolated from clinical samples in our laboratory were tested against the Triclosan coated and non-coated sutures commercially available. Result: Zone of inhibition was found with Triclosan coated suture and no zone of inhibition found with non coated sutures. Conclusion- Usage of sutures coated with antimicrobial agents like Triclosan can reduce the rates of surgical site infection.
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三氯生包被缝合线的体外抗菌活性研究
手术部位感染(ssi)最常见的原因是微生物作为本地菌群存在,是大多数医院的常见问题。其中一个危险因素是异物的存在,包括缝合线。具有持续作用的抗菌涂层缝合线的使用可作为无菌技术的有益补充。材料与方法:随机选取本实验室临床样品中分离的MRSA、MRSE、肠球菌、大肠杆菌、克雷伯氏菌和假单胞菌,对市售的三氯生包被缝合线和非包被缝合线进行检测。结果:三氯生包覆缝线有抑制带,非包覆缝线无抑制带。结论-缝合线涂覆三氯生等抗菌药物可降低手术部位的感染率。
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