Change in cerebral blood flow in an acute hepatitis C patient with depressive state while receiving interferon

International Hepatology Communications Pub Date : 1996-10-01 DOI:10.1016/0928-4346(96)00311-8
M. Sasaki , M. Sata , H. Suzuki , Y. Uchimura , S. Murashima , K. Tanaka , N. Uchimura , J. Nakamura , M. Ishibashi , K. Tanikawa
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引用次数: 3

Abstract

Regional cerebral blood flow (rCBF) was measured with single photon emission computed tomography (SPECT) using N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) in a patient with acute hepatitis C who showed depressive state during interferon therapy. During his depressive state the rCBF was decreased markedly in the inferior frontal cortex. This case suggests that psychotic symptoms during IFN therapy may result from decreased rCBF.

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急性丙型肝炎抑郁患者接受干扰素治疗时脑血流量的变化
应用n -异丙基-p-[123I]碘安非他明(123I- imp)，用单光子发射计算机断层扫描(SPECT)测量了干扰素治疗期间出现抑郁状态的急性丙型肝炎患者的局部脑血流量(rCBF)。在抑郁状态下，额叶下皮层rCBF明显减少。本病例提示干扰素治疗期间的精神病症状可能是由rCBF减少引起的。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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International Hepatology Communications
International Hepatology Communications
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Author index Subject index Clinical usefulness of serum HBV DNA measurement with a non radioactive chemiluminescence method A new point mutation in cholinesterase: relationship between multiple mutation sites and enzyme activity The changes of serum soluble HLA-class I and CD8 concentrations during interferon treatment of chronic hepatitis C patients
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