Evaluation of etiological factors and management of puberty menorrhagia

S. Deo, Monica Agrawal, S. Jaiswar, P. Sankhwar, S. Babu, S. Sonalika, Nitu Nigam
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Abstract

Objectives : To evaluate the causes of puberty menorrhagia and effect of hormonal (Progestogens, estrogens and Combined Oral Contraceptive pills) and non-hormonal methods in the management of puberty menorrhagia. Methods : This prospective study included 51 subjects, who presented with puberty menorrhagia to Department of Obstetrics and Gynaecology, King George Medical University, Lucknow from August 2014 to August 2015. Assessment of each case with thorough history, physical examination and laboratory investigations was done. The underlying cause was diagnosed and the relevant treatment started and subjects kept under regular follow up. Results : In 26 (50.98%) subjects, immaturity of hypothalamic pituitary ovarian axis was the main cause of pubertymenorrhagia, 6 (11.76%) subjects had hypothroidism,5 (9.80%) subjects had polycystic ovarian syndrome, 4 (7.8%) subjects had idiopathic thrombocytopenic purpura, 2 (3.9%) subjects had disseminated intravascular coagulopathy, 3 (5.88%) subjects had hyperprolactinemia, 3 (5.88%) subjects had both hypothyroidism and hyperprolactinemia, 2(3.92%) subjects had fibroid uterus. All patients responded to medical management. Conclusion : Puberty menorrhagia is a distressing condition both for the subject as well as her parents. Most of thecases are due to anovulatory cycles which is a self-limiting condition at perimenarchal age group. Counseling and reassurance ofthe subjects is an important part of management. Long term medical treatment is successful in the majority of cases and rarely surgical intervention is required. Blood transfusion is required in a few cases.
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青春期月经过多的病因分析及治疗
目的:探讨青春期月经过多的原因及激素(孕激素、雌激素及复方口服避孕药)和非激素治疗在青春期月经过多中的作用。方法:本前瞻性研究纳入了51例于2014年8月至2015年8月在勒克瑙乔治国王医科大学妇产科就诊的青春期月经过多患者。通过详细的病史、体格检查和实验室调查对每个病例进行评估。诊断出根本原因,开始相关治疗,并定期随访。结果:26例(50.98%)患者中,下丘脑-垂体-卵巢轴发育不成熟是引起青春期月经过多的主要原因,甲状腺功能减退6例(11.76%),多囊卵巢综合征5例(9.80%),特发性血小板减少性紫癜4例(7.8%),弥散性血管内凝血功能障碍2例(3.9%),高泌乳素血症3例(5.88%),甲状腺功能减退和高泌乳素血症3例(5.88%),子宫肌瘤2例(3.92%)。所有患者对医疗管理均有反应。结论:青春期月经过多对患者及其父母都是一种困扰。大多数病例是由于无排卵周期,这是一个自限性的条件,在围绝经期年龄组。对受试者进行心理咨询和安抚是管理的重要组成部分。长期药物治疗在大多数情况下是成功的,很少需要手术干预。少数病例需要输血。
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