Seromucoid and Protein-Bound Hexose as Inflammatory Markers in Sera of COVID-19 Patients

Abstract

Most common inflammatory markers like C-reactive protein, which is a protein produced by the liver in response to inflammation and infection in the body, is used to quantify circulating molecules that are released as a cause of an inflammatory response in clinical studies.   The aim of this study is to estimate the levels of serum seromucoid and protein bound-hexose (PBH) as inflammatory markers in sera of COVID-19 patients in comparison with normal subjects. For this purpose, Thirty COVID-19 patients were selected as control (male and female) in addition to 30 healthy subjects as the control group. The findings indicated that seromucoid and PBH levels were highly significant increase in COVID-19 patients (P< 0.0001) comparing with normal subjects This study provides evidence that, despite some potential physiological differences, the levels of seromucoid and PBH showed no significant differences for both male and female patients. The results from both parameters showed that COVID-19 severity is associated with inflammatory markers.