Use of Low Molecular Weight Antigens of Mycobacterium tuberculosis as a New Skin Test for Specific Diagnosis of Tuberculosis

Davoud Sadeghi Gariz, N. Mosavari
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Abstract

Accepted: 14 Sep, 2016 Abstract Background and Objectives: Tuberculosis (TB) is an infectious disease and about one-third of the world population are infected with latent TB infection. Active TB infection may develop in 5 to10 percent of individuals with latent infection; therefore, detection of latent infection is of great importance in the control of the disease. The aim of this study was to develop a specific skin test based on low molecular weight proteins secreted by M. tuberculosis for detection of M. tuberculosis infection.
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应用结核分枝杆菌低分子量抗原作为一种新的结核病特异性皮肤试验
摘要背景与目的:结核病(TB)是一种传染性疾病,世界上约三分之一的人口感染潜伏性结核病。潜伏感染的个体中可能有5%至10%出现活动性结核感染;因此,检测潜伏感染对控制该病具有重要意义。本研究的目的是开发一种基于结核分枝杆菌分泌的低分子量蛋白的特异性皮肤试验,用于检测结核分枝杆菌感染。
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