Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis

A. Primasari, Yumi Lindawati, Irma Ervina
{"title":"Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis","authors":"A. Primasari, Yumi Lindawati, Irma Ervina","doi":"10.9790/0853-1607011719","DOIUrl":null,"url":null,"abstract":"‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"37 23","pages":"17-19"},"PeriodicalIF":0.0000,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Dental and Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/0853-1607011719","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
牙龈炎和牙周炎患者唾液钙和钙素水平的改变
唾液蛋白对牙釉质羟基磷灰石钙再矿化有重要影响。石蜡蛋白是结合唾液中羟基磷灰石钙的最强蛋白。牙龈及牙周感染可引起凝血素及钙水平的改变。因此,研究人员希望确定并比较牙龈炎和牙周病患者唾液中施他汀素和钙的水平,主要以印度尼西亚人为研究对象,作为初步数据,探讨施他汀素和钙对牙龈炎和牙周病患者的影响。采用吐痰法采集牙龈炎、牙周病患者全唾液54份;年龄20-50岁,3个月内没有抗生素治疗,不吸烟,不嚼槟榔,没有怀孕、哺乳期、月经。酶联免疫吸附法测定施他汀素水平,分光光度法测定钙水平。结果牙龈炎和牙周病患者唾液中施他汀素平均浓度分别为1.79 ug / ml和2.73 ug / ml,牙龈炎和牙周病患者唾液中钙的平均浓度分别为5.31 mmol/l和0.18 mmol/l。Spearman相关检验从两组样本中得出了两种不同的结果。牙龈炎组患者唾液中钙含量与statherin含量无相关性(p> 0.01),牙周病组患者唾液中钙含量与statherin含量有显著相关性(p< 0.05)。结果表明,虽然两者都是唾液排泄的结果(凝血素和钙),但结果表明,不同的感染,表现出不同的结果。这些结果表明,在这两种感染中存在不同的机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Persistent Enlarged Thymus in an Adult Human Cadaver Choledocholithiasis And Acute Cholangitis Following PostCholecystectomy Clip Migration Paraduodenal Hernia: A Rare Case Report A Study on Hematological Abnormalities in Chronic Liver Diseases Screening of Risk Factors of Hypertension among Urban and Rural Populations of District-Hapur
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1