Helicobacter pylori eradication by low‐dose rifabutin triple therapy (RHB‐105) is unaffected by high body mass index

GastroHep Pub Date : 2021-09-28 DOI:10.1002/ygh2.494
J. Kao, J. Almenoff, Dana D. Portenier, Kely L. Sheldon
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Abstract

Helicobacter pylori infection affects ~35% of Americans and may lead to serious sequelae if left untreated, including gastric cancer. Obesity is a significant risk factor for antibiotic treatment failure; however, little work has been done to understand the influence of high body mass index (BMI) on the success rates of H pylori eradication regimens in treatment‐naïve and refractory adult patients.
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低剂量瑞法布汀三联疗法(RHB - 105)根除幽门螺杆菌不受高体重指数的影响
幽门螺杆菌感染影响约35%的美国人,如果不及时治疗,可能导致严重的后遗症,包括胃癌。肥胖是抗生素治疗失败的重要危险因素;然而,关于高体重指数(BMI)对治疗naïve和难治性成人患者幽门螺杆菌根除方案成功率的影响的研究很少。
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