Thorsten Horn, Kalin D. Narov, Kristen A. Panfilio
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引用次数: 1
Abstract
dsRNA Uptake
In article 2100064 by Kristen A. Panfilio and co-workers, the cuticle exoskeleton of flour beetle larvae reveals normal anatomy (above: head-to-tail in blue-to-red) and long-term parental RNAi knockdown (below), here showing a mirror-image duplication of the abdomen (red termini to yellow center). Strong knockdown can persist for months despite transmission of full-length double-stranded RNA (dsRNA) from the mother into the egg, depleting maternal dsRNA levels.
在Kristen a . Panfilio及其同事的2100064篇文章中，粉甲虫幼虫的表皮外骨骼显示出正常的解剖结构(上图:从头到尾从蓝色到红色)和长期的亲本RNAi缺失(下图)，这里显示了腹部的镜像复制(红色末端到黄色中心)。尽管全长双链RNA (dsRNA)从母体传播到卵子，耗尽母体dsRNA水平，但强敲低可以持续数月。
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