ChemInform Abstract: Crystal Structure of a 1,4-Dihydropyridine with Enantiomers Showing Opposite Effects on Calcium Channels: Structural Features of Calcium Channel Agonists and Antagonists.
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引用次数: 0
Abstract
While (S)-(I) (space group Cc, Z=4) enhances Ca2+ influx across the cell membrane (agonist) the (R)-enantiomer acts oppositely as an antagonist, causing relaxation of smooth muscle.
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