Radiation-induced changes in the brain following stereotactic irradiation evaluated by sequential MRI

Noriaki Tomura, Junichi Izumi, Ikuo Sakuma, Satoshi Takahashi, Koichi Omachi, Takahiro Otani, Akira Anbai, Jiro Watarai, Akira Suzuki, Kazuo Mizoi
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引用次数: 4

Abstract

In 216 patients who underwent stereotactic irradiation (STI), MRI was performed 4–12 times for 17–29 months after STI. Frequency of new radiation-induced lesions more than 2 cm in diameter on sequential MRI following STI, and characteristics on sequential MRI findings were investigated. Ten patients displayed new lesions following STI. These patients comprised eight of 208 patients with intracranial neoplasm and two of seven patients with AVM. Lesions appeared 1–12 months after STI. The lesions appeared near primary lesions in nine patients. Contrast-enhancement was seen along the cerebral cortex in three patients. Sequential MRI is effective in detecting radiation-induced lesions following STI.

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序贯MRI评估立体定向照射后脑内辐射引起的变化
216例接受立体定向照射(STI)的患者,在STI后17-29个月进行了4-12次MRI检查。研究STI后序贯MRI上新发辐射诱发病变直径大于2cm的频率及序贯MRI表现特征。10例患者在性病后出现新的病变。这些患者包括208例颅内肿瘤患者中的8例和7例AVM患者中的2例。性病灶出现于性病后1-12个月。9例患者病灶出现在原发病灶附近。3例患者沿大脑皮层可见对比增强。序贯MRI可有效检测STI后辐射诱发的病变。
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