Long-term Survival of Corneal Sutures: Mersilene vs Nylon

Lindsey F.F. Smith, Charles E. Hugkulstone
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引用次数: 3

Abstract

OBJECTIVE: To investigate the long-term survival of mersilene corneal sutures and compare it with nylon. STUDY DESIGN: Recall of patients from a randomized study of cataract extraction, after a minimum interval of 2 years following surgery. SETTING: Teaching hospital. PATIENTS: Patients who underwent uncomplicated extra-capsular cataract extraction with lens implantation by a single surgeon through a corneal incision closed with mersilene or nylon. MAIN OUTCOME MEASURES: Symptoms attributable to the corneal suture, presence of giant papillary conjunctivitis (GPC) and condition of the suture. RESULTS: All 16 eligible patients in the mersilene group and 16 (80%) of the nylon group were reviewed. The two groups were similar in age, sex distribution and time from surgery. In the nylon group, three patients were symptomatic and one had GPC, compared to none in the mersilene group. All of the mersilene sutures were intact, compared to only four (25%) of the nylon group (P = 0.00002). All four of the intact nylon sutures showed visible evidence of degradation whilst none of the mersilene sutures did (P = 0.0004). CONCLUSIONS: Mersilene corneal sutures have a significantly better long-term survival than nylon. Mersilene should be the preferred material for wound closure following cataract surgery.

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角膜缝合线的长期存活:美丝烯与尼龙
目的:探讨美丝丁烯角膜缝合线的远期生存率,并与尼龙缝合线进行比较。研究设计:回顾一项随机研究的白内障摘除患者,术后至少间隔2年。单位:教学医院。患者:由单一外科医生通过用美丝烯或尼龙封闭的角膜切口行无并发症的囊外白内障摘除术并晶状体植入术的患者。主要观察指标:角膜缝合引起的症状、巨大乳头状结膜炎(GPC)的存在和缝合状况。结果:mersilene组16例符合条件的患者和尼龙组16例(80%)患者均被回顾。两组患者在年龄、性别分布和手术结束时间上相似。在尼龙组中,3名患者出现症状,1名患者出现GPC,而在美西林组中没有患者出现GPC。尼龙组只有4条(25%)缝合线完好无损(P = 0.00002)。所有四个完整的尼龙缝合线都显示出明显的降解迹象,而所有的硅酮缝合线都没有(P = 0.0004)。结论:Mersilene角膜缝合线的长期生存率明显优于尼龙缝合线。Mersilene是白内障手术后伤口闭合的首选材料。
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Subject Index Author Index Editorial Scleral Fixation Re-examined by Ultrasound Biomicroscopy Corneal Topography using a New Moiré Image-based System
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