The role of genetics in hypertension

M. Revanasiddappa , Dharmendra Bhadauria
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Abstract

In patients with primary hypertension, elevated blood pressure (BP) is considered to be a consequence of multiple factors. The 2 major factors involved are environmental factors and genes. A steady progress has been made from experimental animal studies to human genetic studies. Except for the rare monogenic hypertensive diseases, the association of genes and BP are yet to be confirmed, and the quest for “the blood pressure gene” continues. This review briefly discusses the role of genetics in HTN.

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基因在高血压中的作用
在原发性高血压患者中,血压升高(BP)被认为是多种因素的结果。两个主要因素是环境因素和基因。从动物实验研究到人类基因研究,取得了稳步的进展。除了罕见的单基因高血压疾病外,基因与血压的关系尚未得到证实,对“血压基因”的探索仍在继续。本文就遗传学在HTN中的作用作一综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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