Serum Bilirubin Levels and Disease Severity in Patients with Pneumoconiosis.

IF 2.1 4区医学 Q3 RESPIRATORY SYSTEM Canadian respiratory journal Pub Date : 2023-01-01 DOI:10.1155/2023/5642040

You-Fan Peng, Jun-Hua Deng, Xiao-Ying Huang, Qing-Song Zhang

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Abstract

Aim: To investigate the association between serum bilirubin and disease severity in patients with pneumoconiosis.

Methods: The study comprised 45 patients with pneumoconiosis retrospectively; all pneumoconiosis patients were classified into I, II, and III stage according to the radiological severity.

Results: Serum direct bilirubin levels were significantly lower in III stage pneumoconiosis patients than those in I/II stage (p = 0.012) but not serum indirect bilirubin. Serum direct bilirubin was negatively correlated with radiological severity in patients with pneumoconiosis (r = -0.320; p = 0.032); by multiple linear-regression analysis, we observed that serum direct bilirubin levels had independent association with radiological severity in patients with pneumoconiosis (beta = -0.459; p = 0.005).

Conclusions: Serum direct bilirubin levels are negatively associated with disease severity in patients with pneumoconiosis.

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尘肺患者血清胆红素水平与疾病严重程度。

目的:探讨尘肺患者血清胆红素水平与病情严重程度的关系。方法:对45例尘肺患者进行回顾性分析;所有尘肺患者根据放射学严重程度分为ⅰ、ⅱ、ⅲ期。结果:III期尘肺患者血清直接胆红素水平显著低于I/II期(p = 0.012)，而间接胆红素水平无显著差异。尘肺患者血清直接胆红素与放射学严重程度呈负相关(r = -0.320;p = 0.032);通过多元线性回归分析，我们发现尘肺患者血清直接胆红素水平与放射学严重程度有独立相关性(β = -0.459;p = 0.005)。结论:尘肺患者血清直接胆红素水平与疾病严重程度呈负相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Canadian respiratory journal 医学-呼吸系统

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Canadian Respiratory Journal is a peer-reviewed, Open Access journal that aims to provide a multidisciplinary forum for research in all areas of respiratory medicine. The journal publishes original research articles, review articles, and clinical studies related to asthma, allergy, COPD, non-invasive ventilation, therapeutic intervention, lung cancer, airway and lung infections, as well as any other respiratory diseases.