{"title":"Novel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers.","authors":"Tiantian Shi, Edward J Miller","doi":"10.1007/s12410-023-09574-4","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>The purpose of this paper is to provide a focused update on recent advances in non-18F-FDG radiotracers for myocardial inflammatory diseases, with a focus on cardiac sarcoidosis and myocarditis.</p><p><strong>Recent findings: </strong>Novel radiotracers targeting molecular features of inflammation have the potential to visualize underlying molecular mechanisms key to the pathogenesis of inflammatory cardiomyopathies such as sarcoidosis and myocarditis. These radiotracers may provide unique opportunities for improved mechanistic insight, higher specificity, and better quantification of disease activity, as well as potential for guidance and monitoring of immunomodulatory therapies.</p><p><strong>Summary: </strong>Novel radiotracers provide unique possibilities in diagnosis, prognostic performance, and therapy guidance for cardiac sarcoidosis and myocarditis.</p>","PeriodicalId":51842,"journal":{"name":"Current Cardiovascular Imaging Reports","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996562/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cardiovascular Imaging Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12410-023-09574-4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: The purpose of this paper is to provide a focused update on recent advances in non-18F-FDG radiotracers for myocardial inflammatory diseases, with a focus on cardiac sarcoidosis and myocarditis.
Recent findings: Novel radiotracers targeting molecular features of inflammation have the potential to visualize underlying molecular mechanisms key to the pathogenesis of inflammatory cardiomyopathies such as sarcoidosis and myocarditis. These radiotracers may provide unique opportunities for improved mechanistic insight, higher specificity, and better quantification of disease activity, as well as potential for guidance and monitoring of immunomodulatory therapies.
Summary: Novel radiotracers provide unique possibilities in diagnosis, prognostic performance, and therapy guidance for cardiac sarcoidosis and myocarditis.
期刊介绍：
Cardiovascular imaging technologies now play an expanded role in clinical practice. Beyond the diagnosis of a disease process, these techniques are rapidly transitioning to help guide therapy. The journal aims to keep readers current with rapidly evolving advances in instrumentation and imaging procedures that support the expanded role of these technologies in clinical practice. The journal intends to place the entire area of cardiovascular imaging in its proper prospective by establishing the indications and limitations of each imaging technique and by summarizing recent clinical advances.
We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field, including cardiac magnetic resonance, nuclear imaging, echocardiography, cardiac computed tomography, intravascular, molecular, and hybrid imaging. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of internationally diverse members ensures that topics include emerging research and suggests topics of special interest to their country/region. We also provide commentaries from well-known figures in the field.
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