Anna P Kenyon , C Nelson Piercy , J Girling , C Williamson , R.M Tribe , A.H Shennan
{"title":"Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis","authors":"Anna P Kenyon , C Nelson Piercy , J Girling , C Williamson , R.M Tribe , A.H Shennan","doi":"10.1016/S0306-5456(01)00281-9","DOIUrl":null,"url":null,"abstract":"<div><p>Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.</p></div>","PeriodicalId":75620,"journal":{"name":"British journal of obstetrics and gynaecology","volume":"108 11","pages":"Pages 1190-1192"},"PeriodicalIF":0.0000,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0306-5456(01)00281-9","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of obstetrics and gynaecology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0306545601002819","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.
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