Lumbar Disc Herniation: A Controlled, Prospective Study with Ten Years of Observation

Henrik Weber MD
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引用次数: 51

Abstract

Two hundred eighty patients with herniated lumbar discs, verified by radiculography, were divided into three groups. One group, which mainly will be dealt with in this paper, consisted of 126 patients with uncertain indication for surgical treatment, who had their therapy decided by randomization which permitted comparison between the results of surgical and conservative treatment. Another group comprising 67 patients had symptoms and signs that beyond doubt, required surgical therapy. The third group of 87 patients was treated conservatively because there was no indication for operative intervention. Follow-up examinations in the first group were performed after one, four, and ten years.

The controlled trial showed a statistically significant better result in the surgically treated group at the one-year follow-up examination. After four years the operated patients still showed better results, but the difference was no longer statistically significant. Only minor changes took place during the last six years of observation.

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腰椎间盘突出症:一项10年观察的对照前瞻性研究
280例腰椎间盘突出患者经神经根造影证实,分为三组。其中一组是126例手术适应症不确定的患者,采用随机分组的方法,将手术治疗和保守治疗的结果进行比较。另一组包括67名患者,其症状和体征无疑需要手术治疗。第三组87例患者因无手术干预指征而保守治疗。第一组在1年、4年和10年后进行随访检查。对照试验显示,手术治疗组在一年随访检查中有统计学意义的更好的结果。四年后,手术患者仍然表现出更好的结果,但差异不再具有统计学意义。在过去六年的观察中,只发生了微小的变化。
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