Centered endovascular irradiation to prevent postangioplasty restenosis of arteriovenous fistula in hemodialysis patients

Cardiovascular radiation medicine Pub Date : 2004-01-01 DOI:10.1016/j.carrad.2004.02.005

Karsten Krueger , Mark Bendel , Markus Zaehringer , Guido Reinicke , Klaus Lackner

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引用次数: 4

Abstract

Purpose

To report follow-up results of a prospective trial on centered endovascular gamma-irradiation (CEGI) after percutaneous transluminal angioplasty (PTA) for stenosis of arteriovenous fistula in hemodialysis patients.

Methods and materials

Eight patients receiving PTA for recurrent (n=4) or de novo arteriovenous fistula stenoses were treated with CEGI with iridium-192 (14 Gy). Angiography was performed after 6 and 12 months or if problems reoccurred during hemodialysis. Parameters of hemodialysis and duplex sonography were determined the day before and after PTA and after 1, 3, 6, 9, and 12 months.

Results

CEGI was performed successfully and without complications in seven patients. In six patients, restenosis occurred 6–52 weeks (mean 20.8±17.9 weeks) after PTA and required PTA. Parameters of hemodialysis and duplex sonography deteriorated during follow-up.

Conclusions

Centered endovascular gamma-irradiation with iridium 192 immediately after PTA of fistula stenoses was a safe and feasible method but did not prevent restenosis.

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中心血管内照射预防血液透析患者血管成形术后动静脉瘘再狭窄

目的报道经皮腔内血管成形术(PTA)后中心血管内伽马辐照(CEGI)治疗血液透析患者动静脉瘘狭窄的前瞻性随访结果。方法与材料8例接受PTA治疗的复发性或新发动静脉瘘患者(n=4)采用含铱-192 (14 Gy)的CEGI治疗。在6个月和12个月后或血液透析期间再次出现问题时进行血管造影。分别于PTA术前、术后1、3、6、9、12个月测定血液透析及超声参数。结果7例患者行scegi手术成功，无并发症发生。6例患者在PTA和需要PTA后6-52周(平均20.8±17.9周)发生再狭窄。随访期间血液透析及双超参数恶化。结论瘘管狭窄PTA术后立即行血管内γ - 192放射治疗安全可行，但不能预防再狭窄。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cardiovascular radiation medicine

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