Evolution of Liver Transplantation Over the Last 2 Decades Based on a Single-Center Experience of 300 Cases.

IF 1.1 4区 医学 Q3 SURGERY Annals of Transplantation Pub Date : 2023-11-14 DOI:10.12659/AOT.941796
Akihiko Soyama, Takanobu Hara, Hajime Matsushima, Hajime Imamura, Mampei Yamashita, Tomohiko Adachi, Satoshi Miuma, Hisamitsu Miyaaki, Kazuhiko Nakao, Susumu Eguchi
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Abstract

BACKGROUND Over the past 2 decades, there have been many medical advances in the field of liver transplantation. We conducted this study to evaluate the changes in liver transplantation over the last 2 decades. MATERIAL AND METHODS Three hundred cases of liver transplantation encountered between 1997 and 2019 in Nagasaki University Hospital were divided into 3 groups: Era 1 (cases no. 1-100), Era 2 (cases no. 101-200), and Era 3 (cases no. 201-300). Several items were compared among the groups. RESULTS There were no cases of deceased-donor liver transplantation in Era 1, 1 case in Era 2, and 12 cases in Era 3. The proportion of virus-related disease was significantly lower in Era 3 compared to other eras. In contrast, the proportion of alcoholic liver cirrhosis was significantly higher in Era 3 (27%) than Era 1 (7%) and Era 2 (10%) (P<0.01). In Era 1, the right lobe was selected most frequently, but in Eras 2 and 3, the left lobe was more frequently selected. CONCLUSIONS The evolution of the treatment and the transplant system in Japan is clearly reflected in the indications and types of donors for liver transplantation, even at a single center in Japan.

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基于300例单中心经验的肝移植在过去20年的演变。
在过去的二十年中,肝移植领域取得了许多医学进展。我们进行这项研究是为了评估过去20年来肝移植的变化。材料与方法将1997 ~ 2019年长崎大学附属医院收治的肝移植病例300例分为3组:第1期(第2期);1-100), Era 2(病例编号:101-200)和Era 3(病例编号:201 - 300)。在组间比较了几个项目。结果1期无死亡供肝移植病例,2期1例,3期12例。与其他时代相比,第3时代病毒相关疾病的比例明显较低。相比之下,第3期酒精性肝硬化的比例(27%)明显高于第1期(7%)和第2期(10%)
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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation. Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time to first decision is around 3-4 weeks. Time to publication of accepted manuscripts continues to be shortened, with the Editorial team committed to a goal of 3 months from acceptance to publication. Expert reseachers and clinicians from around the world contribute original Articles, Review Papers, Case Reports and Special Reports in every pertinent specialty, providing a lot of arguments for discussion of exciting developments and controversies in the field.
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