Evaluation of risk factors for foot ulceration in individuals with chronic kidney disease.

IF 1.4 4区医学 Q3 DERMATOLOGY Wounds : a compendium of clinical research and practice Pub Date : 2023-10-01

Vacide Aşık Özdemir, Nesrin Nural

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Abstract

Introduction: CKD, like DM, is an independent risk factor for the development and course of foot ulcers.

Objective: The authors studied the incidence and risk factors of foot ulceration in patients with CKD and with or without DM and in patients receiving or not receiving HD.

Materials and methods: Patients with or without DM and with renal failure were divided into 4 groups of 40 patients each according to whether or not they were receiving HD. Data were collected using a patient information form, physical examination of the foot, and risk assessment forms.

Results: Lower extremity ulceration was highest in group 3 (HD+DM+) (15% [6 of 40]), that is, in patients with CKD and DM receiving HD (P = .421). Patients in group 3 were at highest risk for foot ulcers (72.5%) compared with other groups (P = .001). Risk factors associated with foot ulceration were advanced stage (ie, stage 4 or 5) CKD, HD treatment, age, BMI, history of lower extremity ulceration and/or amputation, foot deformities, skin and nail pathology, neuropathy, and vascular insufficiency.

Conclusions: Patients with CKD receiving HD are at high risk for foot ulcers, and this risk increases with the presence of DM.

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慢性肾脏疾病患者足部溃疡的危险因素评估

简介:CKD与DM一样，是足部溃疡发展和病程的独立危险因素。目的:研究CKD合并或不合并DM患者、接受或未接受HD患者足部溃疡的发生率及危险因素。材料与方法:将合并或不合并DM、合并肾功能衰竭的患者根据是否接受HD分为4组，每组40例。使用患者信息表、足部体格检查和风险评估表收集数据。结果:组3 (HD+DM+)下肢溃疡发生率最高(15%[6 / 40])，即CKD和DM合并HD患者下肢溃疡发生率最高(P = .421)。与其他组相比，第3组患者发生足部溃疡的风险最高(72.5%)(P = 0.001)。与足部溃疡相关的危险因素有:CKD晚期(即4期或5期)、HD治疗、年龄、BMI、下肢溃疡和/或截肢史、足部畸形、皮肤和指甲病理、神经病变和血管功能不全。结论:CKD合并HD的患者发生足部溃疡的风险较高，并且这种风险随着DM的存在而增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wounds : a compendium of clinical research and practice 医学-皮肤病学

CiteScore

1.50

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.