Histomorphological Evaluation of Non-Neoplastic Lesions of Uterine Cervix and a Correlation of the Lesion with the Clinical Factors.

Q2 Medicine Cardiovascular and Hematological Agents in Medicinal Chemistry Pub Date : 2023-01-01 DOI:10.2174/1871525720666220603111328

Prem Charles Dhanaraj, Manohar Ulaganathan, Remya Rajan Renuka, Rajesh Pandiyan, Panneerselvam Periasamy

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Abstract

Aim: This study investigates the prevalence of non-malignant lesions of the cervix among various biopsy samples.

Methods: This case study consists of 50 cases of cervical biopsy over almost two years. The case history and clinical details of the patients were obtained.

Results: 60% of the cases that participated in this study reported white discharge per vaginum as a common clinical symptom. 4 cases (8%) showed koilocytic changes specific to the human papillomavirus during the study. Only 2% of the non-specific cervicitis showed lymphoid aggregates. Endocervical changes projected papillary endocervicitis with 9 cases (18%), squamous metaplasia with 7 cases (14%), and nabothian follicle cyst with 3 cases (6%).

Conclusion: It has been concluded that 50 cases were studied histologically, which had adequate representation of both ecto and endocervical tissue. Moreover, 31-40 years of age of patients showed the highest percentage of non-neoplastic lesions of the cervix when compared to other age groups.

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宫颈非肿瘤性病变的组织形态学评价及其与临床因素的关系。

目的:本研究探讨宫颈非恶性病变在不同活检样本中的患病率。方法:本病例研究包括近两年50例宫颈活检。获得患者的病史和临床资料。结果:60%参与本研究的病例报告阴道白色分泌物是常见的临床症状。4例(8%)出现人乳头瘤病毒特异性的空泡细胞改变。仅2%的非特异性宫颈炎表现为淋巴样聚集。宫颈内膜变化提示乳头状宫颈内膜炎9例(18%)，鳞状化生7例(14%)，纳波提安卵泡囊肿3例(6%)。结论:对50例患者进行了组织学研究，对宫颈外腔和宫颈内组织均有充分的代表性。此外，与其他年龄组相比，31-40岁的患者子宫颈非肿瘤性病变的比例最高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiovascular and Hematological Agents in Medicinal Chemistry Medicine-Cardiology and Cardiovascular Medicine

CiteScore

2.70

自引率

0.00%

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期刊介绍： Cardiovascular & Hematological Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new Cardiovascular & Hematological Agents. Each issue contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics in Cardiovascular & Hematological medicinal chemistry. Cardiovascular & Hematological Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cardiovascular & hematological drug discovery.