"An Unusual Pattern of Metastasis" Metastatic Malignant Thymoma Presented with Breast Lump: A Case Report and Literature Review.

IF 0.6 Q4 SURGERY Case Reports in Surgery Pub Date : 2023-01-01 DOI:10.1155/2023/3114843
Kah-Seng Khoo, Kavinya Diana T Nadesalingam, Diana Bee-Lan Ong, Li-Ying Teoh, Mei-Sze Teh, Suniza Jamaris, Mee-Hoong See
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Abstract

Metastatic lesions to the breast from extramammary malignant neoplasms are rare and reported account for 0.5-6.6% of all breast malignancies. Distant metastasis of thymoma is even rarer, especially to extrathoracic regions. We reported a woman with invasive malignant thymoma postneoadjuvant and resection of the thymoma, who developed breast metastasis 7 years later. Breast imaging showed high-density lesion with no intralesional microcalcifications and no significant axillary lymphadenopathy. Core biopsy and histopathology proved the lesion to be metastatic thymic carcinoma. Despite rarity, breast lumps with underlying extramammary malignancy should raise the suspicious of breast metastasis.

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“一种不寻常的转移模式”转移性恶性胸腺瘤表现为乳房肿块:1例报告及文献复习。
乳腺外恶性肿瘤对乳腺的转移性病变是罕见的,据报道占所有乳腺恶性肿瘤的0.5-6.6%。胸腺瘤的远端转移更为罕见,尤其是胸外区域。我们报告了一名浸润性恶性胸腺瘤的妇女,在新辅助手术和胸腺瘤切除术后,7年后发生乳房转移。乳腺影像学显示高密度病变,无病灶内微钙化,无明显腋窝淋巴结病变。核心活检及组织病理学证实病灶为转移性胸腺癌。尽管罕见,但伴有潜在乳腺外恶性肿瘤的乳房肿块应引起对乳腺转移的怀疑。
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