Selective Adenosine A2A Agonists May Change Myocardial Perfusion Imaging.

Kazuya Takehana
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Abstract

In recent years, the requirement for pharmacological stress myocardial perfusion imaging (SPECT) has increased, and adenosine stress testing is now the mainstream. Selective adenosine A2A receptor agonists will be applied clinically in the future. By selectively activating only A2A receptors, it can reduce complications such as bronchospasm, hypotension, and bradycardia, which have been problems with adenosine stress tests. In addition, since this drug can be administered in bolus injection, it has the advantage of being able to perform the test at one root.

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选择性腺苷A2A激动剂可能改变心肌灌注成像。
近年来,对药理学应激心肌灌注成像(SPECT)的需求不断增加,腺苷应激测试已成为主流。选择性腺苷A2A受体激动剂将在未来的临床应用。通过选择性地激活A2A受体,它可以减少并发症,如支气管痉挛、低血压和心动过缓,这些都是腺苷压力测试的问题。此外,由于这种药物可以进行大剂量注射,它的优点是能够在一个根上进行测试。
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