Recent advances of medical biosensors for clinical applications

Yeşeren Saylan, Erdoğan Özgür, Adil Denizli
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引用次数: 5

Abstract

The determination of clinically important biomolecules such as proteins, amino acids, antibodies, enzymes, nucleic acids, hormones and cells is necessary to figure out the physiological and biological functions and also to develop the diagnostics platforms. The improvement of medical biosensors for highly selective, sensitive and rapid biomolecule detection has fundamental significance for clinical diagnostics. Many potential analytical complexities can be smoothly sorted by the biosensors. Health problems have appeared due to the rising population with a risk of chronic diseases such as tuberculosis, prostate, stroke, cardiovascular disease and cancer that require to be deciphered for common health. This review summarizes the importance of medical biosensors for clinical applications, and the use of medical biosensors in the diagnosis of various diseases is extensively discussed with different types of biosensors. Conclusion and future outlooks are mentioned at the end of the review.

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医学生物传感器在临床应用中的最新进展
蛋白质、氨基酸、抗体、酶、核酸、激素、细胞等临床重要生物分子的测定,是了解其生理生物学功能和开发诊断平台的必要条件。提高医用生物传感器的高选择性、高灵敏度、高快速的生物分子检测水平对临床诊断具有重要意义。许多潜在的分析复杂性可以通过生物传感器顺利分类。健康问题出现的原因是,越来越多的人口面临慢性疾病的风险,如结核病、前列腺癌、中风、心血管疾病和癌症,这些疾病需要为公众健康进行解读。本文综述了医学生物传感器在临床应用中的重要性,并结合不同类型的生物传感器广泛讨论了医学生物传感器在各种疾病诊断中的应用。最后对全文进行了总结和展望。
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