Opioid Prescribing Habits of Orthopedic Surgeons Following Total Hip Arthroplasty and Total Knee Arthroplasty: A Pilot Study.

IF 0.6 Q4 PHARMACOLOGY & PHARMACY CANADIAN JOURNAL OF HOSPITAL PHARMACY Pub Date : 2022-01-01 DOI:10.4212/cjhp.3282
Carter VanIderstine, Michael Dunbar, Emily Johnston
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Abstract

Background: Adequate pain management is important in patients' recovery from total hip arthroplasty (THA) and total knee arthroplasty (TKA).

Objective: To determine whether risk factors for prolonged opioid use are considered when discharge prescriptions for postoperative pain are written following THA and TKA.

Methods: Opioid prescriptions written between June 14 and July 9, 2021, for patients who underwent THA or TKA were analyzed. Data were also collected on the patients' age, sex, type of surgery, type of anesthesia (regional or general), preoperative use of opioids, and preoperative use of antidepressants.

Results: Among the 59 patients included in the study, the most common prescriptions were for hydromorphone 2 mg (n = 15, 25%) and hydromorphone 1 mg (n = 15, 25%). At discharge, patients received a median of 400 morphine milligram equivalents (MMEs). There was no significant difference in the quantity of opioids (MMEs) prescribed at discharge in relation to surgery type (p = 0.63), sex (p = 0.44), preoperative antidepressant use (p = 0.22), or preoperative opioid use (p = 0.97). There also appeared to be no correlation between a patient's age and MMEs at discharge (p = 0.21; r 2 = 0.028). None of these variables could be used to predict which patients would receive more than 400 MMEs.

Conclusions: Patient-specific factors appeared not to be taken into consideration when opioids were prescribed for postoperative pain among patients who underwent THA or TKA.

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全髋关节置换术和全膝关节置换术后骨科医生阿片类药物处方习惯的初步研究
背景:充分的疼痛管理对全髋关节置换术(THA)和全膝关节置换术(TKA)患者的康复非常重要。目的:确定在全髋关节置换术和全髋关节置换术后开具治疗术后疼痛的出院处方时,是否考虑了阿片类药物长期使用的危险因素。方法:分析2021年6月14日至7月9日期间接受THA或TKA患者的阿片类药物处方。还收集了患者的年龄、性别、手术类型、麻醉类型(局部或全身)、术前使用阿片类药物和术前使用抗抑郁药的数据。结果:纳入研究的59例患者中,最常见的处方为氢吗啡酮2mg (n = 15,25%)和氢吗啡酮1mg (n = 15,25%)。出院时,患者接受的吗啡当量中位数为400毫克(MMEs)。出院时处方阿片类药物(MMEs)的数量与手术类型(p = 0.63)、性别(p = 0.44)、术前抗抑郁药使用(p = 0.22)或术前阿片类药物使用(p = 0.97)无关。患者的年龄与出院时的MMEs之间似乎也没有相关性(p = 0.21;r2 = 0.028)。这些变量都不能用来预测哪些患者会接受超过400 mmes。结论:在接受THA或TKA的患者中,当处方阿片类药物治疗术后疼痛时,患者特异性因素似乎没有被考虑在内。
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来源期刊
CANADIAN JOURNAL OF HOSPITAL PHARMACY
CANADIAN JOURNAL OF HOSPITAL PHARMACY PHARMACOLOGY & PHARMACY-
CiteScore
1.10
自引率
0.00%
发文量
64
期刊介绍: The CJHP is an academic journal that focuses on how pharmacists in hospitals and other collaborative health care settings optimize safe and effective drug use for patients in Canada and throughout the world. The aim of the CJHP is to be a respected international publication serving as a major venue for dissemination of information related to patient-centred pharmacy practice in hospitals and other collaborative health care settings in Canada and throughout the world.
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