A Case Report of Acute Severe Necrotizing Pancreatitis following the Johnson & Johnson Vaccine against the Novel SARS-CoV-2.

IF 1 Q4 INFECTIOUS DISEASES Case Reports in Infectious Diseases Pub Date : 2023-01-01 DOI:10.1155/2023/9965435

Ayrton I Bangolo, Mahabuba Akhter, Auda Auda, Rahina Akram, Vignesh K Nagesh, Donnee Athem, Reenu Thomas, Ligaya Tibalan, Mansi Trivedi, Saima Mushtaq, Neha Singh, Pracheta Bagale, Georgemar V Arana, Tayyaba Khan, Shelja Sharma, Swetha Mynedi, Dhara D Patel, Mandeep Saini, Madhurya R Chinthakuntla, Kareem Ahmed, Mary Gad, Srikara Dheer D R Gondhi, Georgemar Arana, Rohini B Gurumoorthy, Simcha Weissman

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Abstract

Acute pancreatitis is an inflammatory condition, which is a leading gastrointestinal cause of hospitalization in the United States. Several conditions are associated with acute pancreatitis. More recently, there have been a few cases reported of acute pancreatitis following the Pfizer-BioNTech COVID-19 mRNA vaccine. To our knowledge, no cases of acute pancreatitis have been yet reported following the Johnson & Johnson's Janssen COVID-19 vaccine (J& J vaccine). Herein we report a 34-year-old male with no significant past medical history admitted with acute necrotizing pancreatitis, the day following the receipt of the J&J vaccine. Based on the Naranjo and the modified Naranjo scale, the patient met the requirements for probable drug induced pancreatitis. This case report has the objective to raise awareness of a potentially severe side effect of the J&J vaccine. We hope to use this case to support screening all patients for previous history of acute pancreatitis before administration of the J& J vaccine.

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强生新型SARS-CoV-2疫苗致急性重症坏死性胰腺炎1例报告

急性胰腺炎是一种炎症性疾病，是美国住院治疗的主要胃肠道原因。几种情况与急性胰腺炎有关。最近，有几例报告了辉瑞- biontech COVID-19 mRNA疫苗后的急性胰腺炎病例。据我们所知，在强生公司的杨森COVID-19疫苗(j&j疫苗)后，尚未报告急性胰腺炎病例。在此，我们报告一名34岁男性，没有明显的既往病史，在接受强生疫苗的第二天因急性坏死性胰腺炎入院。根据Naranjo量表及修改后的Naranjo量表，患者符合可能药物性胰腺炎的要求。本病例报告的目的是提高人们对强生疫苗潜在严重副作用的认识。我们希望用这个病例来支持在注射强生疫苗前筛查所有患者是否有急性胰腺炎病史。

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Case Reports in Infectious Diseases INFECTIOUS DISEASES-

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