Evidence-based guideline for the prevention and management of perioperative infection

IF 3.6 2区医学 Q1 MEDICINE, GENERAL & INTERNAL Journal of Evidence‐Based Medicine Pub Date : 2023-02-28 DOI:10.1111/jebm.12514

Qiaoyu Wang, Mingnan Cao, Hua Tao, Zhimin Fei, Xiufeng Huang, Pixia Liang, Baiyun Liu, Jianping Liu, Xiaoyang Lu, Penglin Ma, Shuyi Si, Shuo Wang, Yuewei Zhang, Yingli Zheng, Lei Zang, Xiao Chen, Zhanjun Dong, Weihong Ge, Wei Guo, Xin Hu, Xin Huang, Ling Li, Jianshu Liang, Baoge Liu, Dong Liu, Linna Liu, Songqing Liu, Xianghong Liu, Liyan Miao, Haixia Ren, Guangzhi Shi, Luwen Shi, Shumei Sun, Xia Tao, Rongsheng Tong, Cheng Wang, Bin Wang, Jincheng Wang, Jingwen Wang, Xiaoling Wang, Xiaoyan Wang, Jian Xie, Shouxia Xie, Hua Yang, Jianxin Yang, Chao You, Hongyi Zhang, Yi Zhang, Chengson Zhao, Qingchun Zhao, Jiangguo Zhu, Bo Ji, Ruichen Guo, Chunhua Hang, Xiaowei Xi, Sheyu Li, Zhicheng Gong, Jianxin Zhou, Rui Wang, Zhigang Zhao

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Abstract

Background

We have updated the guideline for preventing and managing perioperative infection in China, given the global issues with antimicrobial resistance and the need to optimize antimicrobial usage and improve hospital infection control levels.

Methods

We conducted a comprehensive evaluation of the evidence for prevention and management of perioperative infection, based on the concepts of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The strength of recommendations was graded and voted using the Delphi method and the nominal group technique. Revisions were made to the guidelines in response to feedback from the experts.

Results

There were 17 questions prepared, for which 37 recommendations were made. According to the GRADE system, we evaluated the body of evidence for each clinical question. Based on the meta-analysis results, recommendations were graded using the Delphi method to generate useful information.

Conclusions

This guideline provides evidence to perioperative antimicrobial prophylaxis that increased the rational use of prophylactic antimicrobial use, with substantial improvement in the risk-benefit trade-off.

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围手术期感染预防与处理循证指南

鉴于全球抗生素耐药性问题以及优化抗菌药物使用和提高医院感染控制水平的需要，我们更新了中国围手术期感染预防和管理指南。方法采用分级推荐评估、发展与评价(GRADE)系统，对围手术期感染预防与管理证据进行综合评价。采用德尔菲法和名义群法对推荐的强度进行评分和投票。根据专家的反馈意见，对准则进行了修订。结果共编制问题17个，提出建议37条。根据GRADE系统，我们评估了每个临床问题的证据体。根据meta分析结果，采用德尔菲法对建议进行评分，以产生有用的信息。结论:该指南为围手术期抗菌药物预防提供了证据，增加了预防性抗菌药物的合理使用，显著改善了风险-收益权衡。

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来源期刊

Journal of Evidence‐Based Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

11.20

自引率

1.40%

发文量

期刊介绍： The Journal of Evidence-Based Medicine (EMB) is an esteemed international healthcare and medical decision-making journal, dedicated to publishing groundbreaking research outcomes in evidence-based decision-making, research, practice, and education. Serving as the official English-language journal of the Cochrane China Centre and West China Hospital of Sichuan University, we eagerly welcome editorials, commentaries, and systematic reviews encompassing various topics such as clinical trials, policy, drug and patient safety, education, and knowledge translation.