Jordanian Undergraduate Students' Views of Participation in Clinical Trials: The COVID-19 Example.

Mamoun Ahram, Rahaf A Al-Qaryouti, Dania S Qarkash, Omar F Salaymeh, Raghad A Shaqqour
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Abstract

The emergence of the COVID-19 pandemic has necessitated broad public participation in clinical trials. Knowledge of the attitudes of the relatively young would provide a perspective on future representative public enrollment in clinical trials. This study investigated the attitudes of undergraduate university students toward participation in COVID-19 clinical trials and determined the predictors of their attitudes. Using a validated, web-based questionnaire, 61.2% of the 425 respondents had heard about clinical trials before. Web-based media were the main sources of this knowledge. Less than 20% expressed willingness to participate in COVID-19 clinical trials or support the participation of a family member. The predictors were personal and family protection from the disease. On the contrary, being a female, possible political exploitation of the vaccine or drug, and their potential inefficacy were predictors of unwillingness to participate. This study may inform different stakeholders in developing effective study recruitment strategies to combat current and emerging pathogens.

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约旦大学生对参与临床试验的看法:以COVID-19为例
COVID-19大流行的出现要求公众广泛参与临床试验。了解相对年轻人群的态度将为未来临床试验中具有代表性的公众登记提供一个视角。本研究旨在调查大学生参与新冠肺炎临床试验的态度,并确定其态度的预测因素。通过一份经过验证的基于网络的问卷调查,425名受访者中有61.2%之前听说过临床试验。网络媒体是这种知识的主要来源。不到20%的人表示愿意参加COVID-19临床试验或支持家庭成员的参与。预测因素是个人和家庭对疾病的保护。相反,作为女性,疫苗或药物可能被政治利用,以及它们潜在的无效是不愿参与的预示因素。这项研究可以为不同的利益相关者提供信息,以制定有效的研究招募策略,以对抗当前和新出现的病原体。
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来源期刊
CiteScore
3.50
自引率
7.70%
发文量
30
审稿时长
>12 weeks
期刊介绍: The Journal of Empirical Research on Human Research Ethics (JERHRE) is the only journal in the field of human research ethics dedicated exclusively to empirical research. Empirical knowledge translates ethical principles into procedures appropriate to specific cultures, contexts, and research topics. The journal''s distinguished editorial and advisory board brings a range of expertise and international perspective to provide high-quality double-blind peer-reviewed original articles.
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