Predictors of Treatment Response to a Psychoeducational Intervention for Anger in Chronic Moderate-Severe Traumatic Brain Injury.

IF 2.4 4区 医学 Q2 CLINICAL NEUROLOGY Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2023-01-01 DOI:10.1176/appi.neuropsych.21110279
Tessa Hart, Roland D Maiuro, Jesse R Fann, Monica J Vaccaro, Inna Chervoneva
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引用次数: 1

Abstract

Objective: The investigators examined predictors of treatment response to anger self-management training (ASMT) among patients with chronic moderate-severe traumatic brain injury (TBI).

Methods: A multicenter randomized clinical trial comprising 90 participants with moderate-severe TBI was conducted. Fifty-four participants who were randomly assigned to receive active treatment and provided complete data were included in the current secondary analysis. Model averaging was used to examine the relative importance and significance of pretreatment variables for predicting change during treatment. Dependent variables were pre- to posttreatment changes in trait anger (TA) and anger expression-out (AX-O) subscale scores of the State-Trait Anger Expression Inventory-Revised. Predictors included demographic, injury-related, and neuropsychological variables, including both objective and self-reported measures of executive function, as well as readiness to change and participation of a significant other in treatment.

Results: Change in both dependent variables was predicted by higher baseline anger. Greater change in TA was additionally predicted by White race, higher education, shorter posttraumatic amnesia, and worse self-reported (but not objectively measured) executive dysfunction; the latter predictor may have indicated better self-awareness. Greater change in AX-O was additionally predicted by better episodic memory and, paradoxically, lower readiness to change.

Conclusions: Further research should focus on adapting psychoeducational anger treatments to better serve the diverse populations affected by moderate-severe TBI. These findings suggest that providing memory aids to support the use of learned strategies after treatment cessation would be beneficial. Further research should also examine the construct of readiness to change and specific aspects of executive function that may affect treatment response in psychoeducational treatments. These findings were derived from only one model of anger intervention, and the relevance to other treatment approaches cannot be assumed.

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慢性中重度创伤性脑损伤患者愤怒心理教育干预治疗反应的预测因素。
目的:探讨慢性中重度创伤性脑损伤(TBI)患者愤怒自我管理训练(ASMT)治疗反应的预测因素。方法:对90例中重度TBI患者进行多中心随机临床试验。54名随机分配接受积极治疗并提供完整数据的参与者被纳入当前的二次分析。模型平均用于检验预处理变量对预测治疗期间变化的相对重要性和显著性。因变量为状态-特质愤怒表达量表(State-Trait anger Expression Inventory-Revised)的特质愤怒(TA)和愤怒表达-输出(AX-O)分量表得分在治疗前后的变化。预测因素包括人口统计学、损伤相关和神经心理学变量,包括客观和自我报告的执行功能测量,以及改变的准备程度和重要他人参与治疗。结果:两个因变量的变化可以通过基线愤怒的升高来预测。此外,白人种族、高等教育、较短的创伤后失忆症和较差的自我报告(但非客观测量)执行功能障碍也能预测TA的较大变化;后一种预测可能表明了更好的自我意识。此外,更好的情景记忆和更低的改变准备程度也预示着AX-O的更大变化。结论:进一步的研究应侧重于适应心理教育愤怒治疗,以更好地服务于中重度创伤性脑损伤患者的不同人群。这些发现表明,在治疗停止后提供记忆辅助来支持学习策略的使用将是有益的。进一步的研究还应该检查改变准备的结构和执行功能的具体方面,这些方面可能会影响心理教育治疗的治疗反应。这些发现仅来自一种愤怒干预模型,不能假设与其他治疗方法的相关性。
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来源期刊
CiteScore
5.30
自引率
3.40%
发文量
67
审稿时长
6-12 weeks
期刊介绍: As the official Journal of the American Neuropsychiatric Association, the premier North American organization of clinicians, scientists, and educators specializing in behavioral neurology & neuropsychiatry, neuropsychology, and the clinical neurosciences, the Journal of Neuropsychiatry and Clinical Neurosciences (JNCN) aims to publish works that advance the science of brain-behavior relationships, the care of persons and families affected by neurodevelopmental, acquired neurological, and neurodegenerative conditions, and education and training in behavioral neurology & neuropsychiatry. JNCN publishes peer-reviewed articles on the cognitive, emotional, and behavioral manifestations of neurological conditions, the structural and functional neuroanatomy of idiopathic psychiatric disorders, and the clinical and educational applications and public health implications of scientific advances in these areas. The Journal features systematic reviews and meta-analyses, narrative reviews, original research articles, scholarly considerations of treatment and educational challenges in behavioral neurology & neuropsychiatry, analyses and commentaries on advances and emerging trends in the field, international perspectives on neuropsychiatry, opinions and introspections, case reports that inform on the structural and functional bases of neuropsychiatric conditions, and classic pieces from the field’s rich history.
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