[Medical Care of people living with HIV in the Instituto Mexicano del Seguro Social].

Sandra Carlota Treviño-Pérez, Alfonso Vega-Yáñez, Christian Ivan Martínez-Abarca, Guadalupe Estrada-Zarazúa, Luis Alberto Pérez-Camargo, Gabriela Borrayo-Sánchez
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Abstract

Infection by the human immunodeficiency virus (HIV) is apublic health problem worldwide, however, the incidence has remained relatively stable. In Mexico, around 10,000 new cases are reported each year. The Instituto Mexicano del Seguro Social (IMSS) has been a pioneer in the care of people living with HIV (PLWHA), gradually incorporating the different antiretroviral drugs (ARV). The first ARV used at the institutional level was zidovudine, in the 1990s, and later other agents were incorporated, such as protease inhibitors, drugs from the group of non-nucleoside analogs, and integrase inhibitors. In 2020, the migration to ARV schemes coformulated in a single tablet based on integrase inhibitors, which constitute a highly effective option and timely supply of drugs has been achieved in 99% of the population. In the aspect of prevention, the IMSS has also been a pioneer by being the first institution to implement HIV pre-exposure prophylaxis in 2021 at the national level and since 2022 universal post-exposure prophylaxis is available. The IMSS continues to be at the forefront incorporating the use of different management tools and instruments for the benefit of the population living with HIV. This document summarizes the history of HIV in the IMSS from the beginning of the epidemic to the present time.

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[墨西哥社会研究所对艾滋病毒感染者的医疗护理]。
人类免疫缺陷病毒(HIV)感染是世界范围内的一个公共卫生问题,但其发病率一直保持相对稳定。在墨西哥,每年约有1万例新病例报告。墨西哥社会保健研究所(IMSS)一直是照顾艾滋病毒感染者(PLWHA)的先驱,逐步采用不同的抗逆转录病毒药物(ARV)。在20世纪90年代,第一个在机构层面使用的抗逆转录病毒药物是齐多夫定,后来加入了其他药物,如蛋白酶抑制剂、非核苷类似物类药物和整合酶抑制剂。到2020年,99%的人口实现了向以整合酶抑制剂为基础的片剂联合配制的抗逆转录病毒方案的迁移,这是一种非常有效的选择,并能及时提供药物。在预防方面,IMSS也是一个先锋,于2021年在国家一级率先实施艾滋病毒暴露前预防,并自2022年起提供普遍的暴露后预防。IMSS继续走在前列,结合使用不同的管理工具和手段,造福艾滋病毒感染者。本文件总结了艾滋病病毒的历史在IMSS从开始流行到现在的时间。
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