S Mohd-Razali, K Ahmad-Affandi, S Ibrahim, A H Abdul-Rashid, N Abdul-Shukor
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引用次数: 0
Abstract
Purpura fulminans (PF) is a severe clinical manifestation of Neisseria meningitides infection that is associated with high mortality rates in children. Survivors are frequently left with debilitating musculoskeletal sequelae. There is a paucity of reports on the musculoskeletal pathology of purpura fulminans. We report on a 2-year-old boy with purpura fulminans due to meningococcemia. The child developed distal gangrene in both the upper and lower limbs. Amputations were done for both lower limbs. Histological examination of the amputated specimens showed an inflammatory process and features of osteonecrosis. The latest follow-up at the age of 6 years showed a right knee valgus due to asymmetrical growth arrest of the proximal tibia. PF and its complications are challenging to treat and may require a multidisciplinary approach to improve patient's functional ability.
期刊介绍：
The Malaysian Orthopaedic Journal is a peer-reviewed journal that publishes original papers and case reports three times a year in both printed and electronic version. The purpose of MOJ is to disseminate new knowledge and provide updates in Orthopaedics, trauma and musculoskeletal research. It is an Open Access journal that does not require processing fee or article processing charge from the authors. The Malaysian Orthopaedic Journal is the official journal of Malaysian Orthopaedic Association (MOA) and ASEAN Orthopaedic Association (AOA).
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