Illuminating the oral microbiome and its host interactions: tools and approaches for molecular ecological studies.

IF 10.1 2区 生物学 Q1 MICROBIOLOGY FEMS microbiology reviews Pub Date : 2023-01-16 DOI:10.1093/femsre/fuac052
Jens Kreth, Justin Merritt
{"title":"Illuminating the oral microbiome and its host interactions: tools and approaches for molecular ecological studies.","authors":"Jens Kreth, Justin Merritt","doi":"10.1093/femsre/fuac052","DOIUrl":null,"url":null,"abstract":"<p><p>A more comprehensive understanding of oral diseases like caries and periodontitis is dependent on an intimate understanding of the microbial ecological processes that are responsible for disease development. With this review, we provide a comprehensive overview of relevant molecular ecology techniques that have played critical roles in the current understanding of human oral biofilm development, interspecies interactions, and microbiome biogeography. The primary focus is on relevant technologies and examples available in the oral microbiology literature. However, most, if not all, of the described technologies should be readily adaptable for studies of microbiomes from other mucosal sites in the body. Therefore, this review is intended to serve as a reference guide used by microbiome researchers as they inevitably transition into molecular mechanistic studies of the many significant phenotypes observed clinically.</p>","PeriodicalId":12201,"journal":{"name":"FEMS microbiology reviews","volume":"47 1","pages":""},"PeriodicalIF":10.1000,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936263/pdf/","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"FEMS microbiology reviews","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1093/femsre/fuac052","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 3

Abstract

A more comprehensive understanding of oral diseases like caries and periodontitis is dependent on an intimate understanding of the microbial ecological processes that are responsible for disease development. With this review, we provide a comprehensive overview of relevant molecular ecology techniques that have played critical roles in the current understanding of human oral biofilm development, interspecies interactions, and microbiome biogeography. The primary focus is on relevant technologies and examples available in the oral microbiology literature. However, most, if not all, of the described technologies should be readily adaptable for studies of microbiomes from other mucosal sites in the body. Therefore, this review is intended to serve as a reference guide used by microbiome researchers as they inevitably transition into molecular mechanistic studies of the many significant phenotypes observed clinically.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
阐明口腔微生物群及其与宿主的相互作用:分子生态学研究的工具和方法。
要想更全面地了解龋齿和牙周炎等口腔疾病,就必须深入了解导致疾病发生的微生物生态过程。通过这篇综述,我们全面概述了相关的分子生态学技术,这些技术在目前了解人类口腔生物膜发展、物种间相互作用和微生物群生物地理学方面发挥了关键作用。主要重点是口腔微生物学文献中的相关技术和实例。不过,大部分(如果不是全部的话)所述技术应可随时用于人体其他粘膜部位微生物组的研究。因此,本综述旨在为微生物组研究人员提供参考指南,因为他们不可避免地要过渡到对临床上观察到的许多重要表型进行分子机理研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
FEMS microbiology reviews
FEMS microbiology reviews 生物-微生物学
CiteScore
17.50
自引率
0.90%
发文量
45
审稿时长
6-12 weeks
期刊介绍: Title: FEMS Microbiology Reviews Journal Focus: Publishes reviews covering all aspects of microbiology not recently surveyed Reviews topics of current interest Provides comprehensive, critical, and authoritative coverage Offers new perspectives and critical, detailed discussions of significant trends May contain speculative and selective elements Aimed at both specialists and general readers Reviews should be framed within the context of general microbiology and biology Submission Criteria: Manuscripts should not be unevaluated compilations of literature Lectures delivered at symposia must review the related field to be acceptable
期刊最新文献
Microbial functional diversity and redundancy: moving forward. Multidisciplinary methodologies used in the study of cable bacteria. Unraveling the genomic diversity of the Pseudomonas putida group: exploring taxonomy, core pangenome, and antibiotic resistance mechanisms. Assembly of functional microbial ecosystems: from molecular circuits to communities. The biochemical mechanisms of plastic biodegradation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1