An Unusual Presentation Of Steven-Johnson Syndrome After Bnt162b2 Covid-19 Vaccination.

Ravi Patel, Victor Lu
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Abstract

We present a 23-year-old white British male that presented to the Accident and Emergency Department, two weeks after the second dose of the BNT162b2 (BioNTech/Pfizer) vaccine. No similar use has been documented previously in literature. We report one potential complication of the Pfizer COVID-19 vaccine: A known case of Stevens-Johnson syndrome (SJS) that occurred after the second dose of the Pfizer COVID-19 vaccine alone without exposure to any other drug. Despite a significantly severe adverse drug reaction, the patient demonstrated completed recovery. The risk of developing severe cutaneous drug reaction from subsequent COVID-19 vaccinations in these patients is still unclear and remains a dilemma to date.

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接种Bnt162b2 Covid-19疫苗后出现罕见的史蒂文-约翰逊综合征
我们报告了一名23岁的英国白人男性,在第二剂BNT162b2 (BioNTech/Pfizer)疫苗后两周就诊于急诊科。在以前的文献中没有类似的用法记录。我们报告辉瑞COVID-19疫苗的一个潜在并发症:在单独接种第二剂辉瑞COVID-19疫苗后未接触任何其他药物而发生史蒂文斯-约翰逊综合征(SJS)的已知病例。尽管出现了严重的药物不良反应,但患者完全康复。这些患者随后接种COVID-19疫苗后发生严重皮肤药物反应的风险尚不清楚,迄今仍是一个难题。
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