A Single-Center Evaluation of Pediatric Measles Cases in Istanbul, Türkiye, in 2019.

IF 1.3 4区 医学 Q4 INFECTIOUS DISEASES Japanese journal of infectious diseases Pub Date : 2023-09-22 Epub Date: 2023-04-28 DOI:10.7883/yoken.JJID.2022.701
Mahmut Caner Us, Kübra Coci, Erkan Akkuş, Berker Okay, Gülşen Akkoç
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Abstract

Although measles can be prevented and eliminated by vaccination, it is a highly contagious viral disease that can lead to serious complications, disability, and death. The aim of this retrospective study was to evaluate the characteristics of measles cases in a single center. All children with clinically suspected measles who attended the Pediatric Clinic at Esenler Maternity and Child Health Hospital in Istanbul, Türkiye, between January 1 and June 30, 2019 were included in the analysis. None of the children with measles were fully vaccinated. The incidence and duration of conjunctivitis were significantly higher in the unvaccinated group than in the partially vaccinated group (P = 0.027 and P = 0.019, respectively). Unvaccinated patients had a significantly lower median leukocyte count (P = 0.019) and significantly higher median C-reactive protein level (P = 0.021). The vitamin A level and leukocyte count were moderately positively correlated (r = 0.698; P = 0.008). Children should be fully vaccinated in order to prevent measles.

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2019年土耳其伊斯坦布尔儿童麻疹病例的单一中心评估。
尽管麻疹可以通过接种疫苗预防和消除,但它是一种高度传染性的病毒性疾病,可能导致严重并发症、残疾和死亡。这项回顾性研究的目的是评估单个中心麻疹病例的特征。2019年1月1日至6月30日期间在土耳其伊斯坦布尔埃森勒妇幼保健医院儿科诊所就诊的所有临床疑似麻疹儿童均被纳入分析。没有一个患麻疹的儿童完全接种了疫苗。未接种疫苗组的结膜炎发生率和持续时间显著高于部分接种疫苗组(分别为P=0.027和P=0.019)。未接种疫苗的患者白细胞计数中位数显著较低(P=0.019),C反应蛋白水平中位数显著较高(P=0.021)。维生素a水平与白细胞计数呈中度正相关(r=0.698;P=0.008)。儿童应完全接种疫苗以预防麻疹。
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来源期刊
CiteScore
4.50
自引率
4.50%
发文量
172
审稿时长
2 months
期刊介绍: Japanese Journal of Infectious Diseases (JJID), an official bimonthly publication of National Institute of Infectious Diseases, Japan, publishes papers dealing with basic research on infectious diseases relevant to humans in the fields of bacteriology, virology, mycology, parasitology, medical entomology, vaccinology, and toxinology. Pathology, immunology, biochemistry, and blood safety related to microbial pathogens are among the fields covered. Sections include: original papers, short communications, epidemiological reports, methods, laboratory and epidemiology communications, letters to the editor, and reviews.
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