Healthcare Management, avoidable mortality, telemedicine to improve health of the diabetic population.

Igiene e sanita pubblica Pub Date : 2022-07-01
Giuseppe Gambale, Marta Castellani, Elisa Mazzeo, Andrea De Giorgi, Rosario Andrea Cocchiara, Giovanni Profico, Simona Amato
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Abstract

Background: Worldwide the International Diabetes Federation (IDF) estimated that in 2021 9.2% of adults (536.6 million, between 20 and 79 years of age) are diabetic and 32.6% under 60 years (6.7 million) die because of diabetes. This disease is set to become the leading cause of disability and mortality by 2030. In Italy, the prevalence of Diabetes is about 5%; in the pre-pandemic period, from 2010 to 2019, diabetes was responsible for 3% of deaths recorded, while during the pandemic in 2020, these deaths increased to about 4%. The present work aimed to measure the outcomes obtained from the ICPs (integrated care pathways) implemented by a Health Local Authority according to the model of the Lazio region and its impact on avoidable mortality, i.e., those deaths potentially avoidable with primary prevention interventions, early diagnosis and targeted therapies, adequate hygienic conditions and proper health care.

Materials and methods: Data from 1675 patients enrolled in the diagnostic treatment pathway were analyzed, 471 with type 1 diabetes and the remainder with type 2 (mean age 17.5 and 69, respectively). 987 patients with type 2 diabetes also had comorbidities: in 43% obesity, 56% dyslipidemia, 61% hypertension, 29% COPD. In 54% they had at least 2 comorbidities. All patients enrolled in the ICPs were equipped with a glucometer and an app capable of recording results on capillary blood, 269 with type 1 diabetes were equipped with continuous and 198 insulin pump measurement devices. All enrolled patients recorded at least one daily blood glucose reading, one weekly weight reading, and recorded steps taken daily. They also underwent glycated hemoglobin monitoring, periodic visits and scheduled instrumental checks. A total of 5500 parameters were measured for patients with type 2 diabetes and 2345 for patients with type 1 diabetes.

Results: Analysis of medical records revealed that 93% of patients with type 1 diabetes were found to be adherent to the treatment pathway, adherence of patients with type 2 diabetes was recorded in 87% of enrolled cases. The analysis of accesses to the Emergency Department for decompensated diabetes saw only 21% of patients enrolled in the ICPs, but recording poor compliance. The mortality in enrolled patients was 1.9% compared with 4.3 percent in patients not enrolled in ICPs, and patients amputated for diabetic foot resulted in 82% of patients not enrolled in ICPs. Finally, it is noted that patients also enrolled in the telerehabilitation pathway or home care rehabilitation (28%), with the same conditions of severity of neuropathic and vasculopathic picture presented a reduction of 18% in leg or lower limb amputation compared to patients not enrolled or not adhering to ICPs, a reduction of 27% in metatarsal amputation and 34% in toes amputation.

Conclusions: Telemonitoring of diabetic patients allows for greater patient empowerment with increased adherence, as well as a reduction in Emergency Department and inpatient admissions, thus resulting in ICPs being a tool for both standardization of quality of care and standardization of the average cost of the chronic patient with diabetic disease. Likewise, telerehabilitation can reduce the incidence of amputations from diabetic foot disease if associated with adherence to the proposed pathway with ICPs.

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医疗保健管理、可避免的死亡率、远程医疗以改善糖尿病人群的健康。
背景:世界范围内,国际糖尿病联合会(IDF)估计,到2021年,9.2%的成年人(5.366亿,年龄在20至79岁之间)患有糖尿病,60岁以下32.6%(670万)死于糖尿病。到2030年,这种疾病将成为导致残疾和死亡的主要原因。在意大利,糖尿病的患病率约为5%;在2010年至2019年大流行前期间,糖尿病导致的死亡人数占所记录死亡人数的3%,而在2020年大流行期间,这些死亡人数增加到约4%。目前的工作旨在衡量地方卫生当局根据拉齐奥地区的模式实施的综合护理途径所取得的成果及其对可避免死亡率的影响,即通过初级预防干预、早期诊断和有针对性的治疗、适当的卫生条件和适当的保健可以避免的死亡。材料和方法:纳入诊断治疗途径的1675例患者的数据进行分析,其中471例为1型糖尿病,其余为2型糖尿病(平均年龄分别为17.5岁和69岁)。987例2型糖尿病患者也有合并症:43%为肥胖,56%为血脂异常,61%为高血压,29%为慢性阻塞性肺病。54%的患者至少有2种合并症。所有参加ICPs的患者都配备了血糖仪和一个能够记录毛细血管血结果的应用程序,269名1型糖尿病患者配备了连续测量装置,198名胰岛素泵测量装置。所有入组的患者每天至少记录一次血糖读数,每周记录一次体重读数,并记录每天的步数。他们还接受了糖化血红蛋白监测,定期就诊和预定的仪器检查。2型糖尿病患者共测量了5500个参数,1型糖尿病患者测量了2345个参数。结果:病历分析显示,93%的1型糖尿病患者坚持治疗途径,87%的2型糖尿病患者坚持治疗途径。对失代偿期糖尿病急诊科就诊情况的分析显示,只有21%的患者参加了ICPs,但依从性较差。入组患者的死亡率为1.9%,未入组患者的死亡率为4.3%,因糖尿病足截肢的患者死亡率为82%。最后,值得注意的是,同样参加远程康复途径或家庭护理康复的患者(28%),与未参加或未坚持ICPs的患者相比,具有相同神经病变和血管病变严重程度的患者,腿部或下肢截肢减少18%,跖骨截肢减少27%,脚趾截肢减少34%。结论:糖尿病患者的远程监测可以提高患者的依从性,并减少急诊科和住院患者的入院率,从而使icp成为糖尿病慢性患者护理质量标准化和平均成本标准化的工具。同样,如果远程康复与ICPs的建议途径相关,则可以减少糖尿病足病截肢的发生率。
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