{"title":"Unusual presentation of a mass and \"cobble-stone like\" changes in the bronchus of a patient with granulomatosis with polyangitis.","authors":"Ping Fan, Zhiming Hao, Peilong Cao, Lan He","doi":"10.2478/rir-2023-0007","DOIUrl":null,"url":null,"abstract":"A 44-year-old male was diagnosed with granulomatosis with polyangiitis (GPA) 1 year ago because of intermittent cough, short of breath, epistaxis, hearing loss and a positive protein-ase-3 anti-neutrophilic cytoplasmatic antibody (PR3-ANCA) test. After being treated with oral prednisone, cyclophospha-mide for a year, he was hospitalized due to reappearance of cough and epistaxis. The nasopharyngoscopy showed extensive necrosis of the left nasal cavity. The biopsy of nasal cavity mucosa revealed fibrinoid necrotizing vasculitis","PeriodicalId":74736,"journal":{"name":"Rheumatology and immunology research","volume":"4 1","pages":"44-45"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/d1/rir-4-1-rir-2023-0007.PMC10150860.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rheumatology and immunology research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/rir-2023-0007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A 44-year-old male was diagnosed with granulomatosis with polyangiitis (GPA) 1 year ago because of intermittent cough, short of breath, epistaxis, hearing loss and a positive protein-ase-3 anti-neutrophilic cytoplasmatic antibody (PR3-ANCA) test. After being treated with oral prednisone, cyclophospha-mide for a year, he was hospitalized due to reappearance of cough and epistaxis. The nasopharyngoscopy showed extensive necrosis of the left nasal cavity. The biopsy of nasal cavity mucosa revealed fibrinoid necrotizing vasculitis